s37194

Gene Symbol:

TET1 KMT2A

Gene Name:

tet methylcytosine dioxygenase 1

lysine methyltransferase 2A

Gene Aliases:

CXXC6, LCX, MLL-TET1, TET1-MLL, bA119F7.1

ALL-1, CXXC7, HRX, HTRX1, MLL, MLL-AF9, MLL/GAS7, MLL1, MLL1A, TET1-MLL, TRX1, WDSTS

Chromosome Location:

Chr.10: 68560360 - 68700794 on Build GRCh38

Chromosome Location:

Chr.11: 118436490 - 118526832 on Build GRCh38

UniGene ID:

Hs.258855

Hs.258855

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: TET1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_030625.2	NP_085128.2	11	5856
	XM_011540204.2	XP_011538506.1	12	5943
	XM_011540205.2	XP_011538507.1	11	3586
	XM_011540207.2	XP_011538509.1	11	3823
	XM_017016686.1	XP_016872175.1	10	3627
	XM_017016687.1	XP_016872176.1	12	3877
	XM_017016688.1	XP_016872177.1	12	3757
	XM_017016689.1	XP_016872178.1	11	3707
GenBank mRNA	AB051463.1	-	8	1148
	AF430147.1	-	11	5560
	AK123436.1	-	8	1770
	AL713658.1	-	2	360
	AL832334.1	-	1	58
	AL832337.1	-	1	58
	JX311858.1	-	9	3043
	JX311859.1	-	7	2858

Gene Symbol: KMT2A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	FM165198.1	-		35

More Information

Gene Ontology Categories:

Process(es)

inner cell mass cell differentiation
transcription, DNA-templated
protein O-linked glycosylation
positive regulation of cell proliferation
covalent chromatin modification
stem cell population maintenance
positive regulation of histone methylation
positive regulation of transcription from RNA polymerase II promoter
oxidation-reduction process
DNA demethylation
negative regulation of methylation-dependent chromatin silencing

Function(s)

iron ion binding
zinc ion binding
structure-specific DNA binding
methylcytosine dioxygenase activity