s41321 Validated

• Gene Symbol: EGLN3
• Gene Name: egl-9 family hypoxia inducible factor 3
• Gene Aliases: HIFP4H3, HIFPH3, PHD3
• Chromosome Location: Chr.14: 33924215 - 33951078 on Build GRCh38
• UniGene ID: Hs.135507
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: EGLN3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001308103.1	NP_001295032.1	3	392
	NM_022073.3	NP_071356.1	3	926
GenBank mRNA	AJ310545.1	-	3	926
	AK025273.1	-	3	926
	AK123350.1	-	4	755
	AK225473.1	-	3	926
	BC010992.2	-	3	882	3948676
	BC064924.1	-	3	886	6141425
	BC102030.1	-	3	392	40032049
	BC105938.1	-	3	392	40032045
	BC105939.1	-	3	674	40032051
	BC111057.1	-	3	909	5747720
	BX346941.2	-	2	249
	DQ975379.1	-	3	326

More Information

Matching Taqman Gene Expression Assay:

Hs00222966_m1

Gene Ontology Categories:

Process(es)

response to hypoxia
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cellular response to DNA damage stimulus
protein hydroxylation
peptidyl-proline hydroxylation to 4-hydroxy-L-proline
regulation of cell proliferation
regulation of neuron apoptotic process
oxidation-reduction process
regulation of transcription from RNA polymerase II promoter in response to hypoxia

Function(s)

iron ion binding
protein binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
L-ascorbic acid binding
peptidyl-proline 4-dioxygenase activity