s4401 Validated

• Gene Symbol: DYRK1A
• Gene Name: dual specificity tyrosine phosphorylation regulated kinase 1A
• Gene Aliases: DYRK, DYRK1, HP86, MNB, MNBH, MRD7
• Chromosome Location: Chr.21: 37365790 - 37515376 on Build GRCh38
• UniGene ID: Hs.368240
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DYRK1A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001396.3	NP_001387.2	9	1422
	NM_101395.2	NP_567824.1	11	1596
	NM_130436.2	NP_569120.1	9	2790
	NM_130438.2	NP_569122.1	9	1423
	XM_005260933.4	XP_005260990.1	5	749
	XM_006723976.3	XP_006724039.1	10	1494
	XM_006723977.3	XP_006724040.1	10	1819
	XM_006723978.3	XP_006724041.1	10	2548
	XM_006723979.3	XP_006724042.1	10	1654
	XM_011529482.2	XP_011527784.1	9	1516
	XM_011529483.2	XP_011527785.1	10	4362
	XM_011529484.2	XP_011527786.1	9	1489
	XM_011529485.2	XP_011527787.1	9	2005
	XM_017028284.1	XP_016883773.1	10	1453
	XM_017028285.1	XP_016883774.1	10	1699
	XM_017028286.1	XP_016883775.1	12	1696
GenBank mRNA	AF108830.1	-	11	1596
	AK301752.1	-	5	762
	D85759.1	-	9	1388
	D86550.1	-	9	2793
	U52373.1	-	9	1422
	U58496.1	-	9	1382

More Information

Matching Taqman Gene Expression Assay:

Hs00176369_m1

Gene Ontology Categories:

Process(es)

regulation of alternative mRNA splicing, via spliceosome
protein phosphorylation
nervous system development
circadian rhythm
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
peptidyl-tyrosine phosphorylation
negative regulation of DNA damage response, signal transduction by p53 class mediator
protein autophosphorylation
negative regulation of mRNA splicing, via spliceosome
positive regulation of protein deacetylation

Function(s)

protein kinase activity
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein binding
ATP binding
identical protein binding
protein self-association
tau protein binding