s4649 Validated

• Gene Symbol: MARK2
• Gene Name: microtubule affinity regulating kinase 2
• Gene Aliases: EMK-1, EMK1, PAR-1, Par-1b, Par1b
• Chromosome Location: Chr.11: 63838928 - 63911020 on Build GRCh38
• UniGene ID: Hs.567261
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MARK2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001039469.2	NP_001034558.2	4, 5	908
	NM_001163296.1	NP_001156768.1	4, 5	908
	NM_001163297.1	NP_001156769.1	4, 5	908
	NM_004954.4	NP_004945.4	4, 5	908
	NM_017490.3	NP_059672.2	4, 5	725
	XM_011544789.1	XP_011543091.1	5, 6	799
	XM_011544790.1	XP_011543092.1	5, 6	799
	XM_011544791.1	XP_011543093.1	5, 6	799
	XM_011544792.1	XP_011543094.1	5, 6	799
	XM_011544793.1	XP_011543095.1	5, 6	799
	XM_011544794.1	XP_011543096.1	5, 6	799
	XM_011544795.1	XP_011543097.1	5, 6	799
	XM_011544796.1	XP_011543098.1	5, 6	799
	XM_011544797.1	XP_011543099.1	5, 6	799
	XM_011544798.1	XP_011543100.1	5, 6	799
	XM_017017310.1	XP_016872799.1	4, 5	881
	XM_017017311.1	XP_016872800.1	5, 6	799
GenBank mRNA	AB188493.1	-	4, 5	912
	AB271694.1	-	3, 4	230
	AF387638.1	-	3, 4	248
	AK225766.1	-	4, 5	743
	AK290339.1	-	4, 5	693
	AK307858.1	-	5, 6	544
	BC008771.2	-	4, 5	300
	BC084540.1	-	4, 5	367	4591688
	BT007342.1	-	3, 4	230
	X97630.1	-	4, 5	637

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_021699, XM_006230887, XM_006230879, XM_006230881, XM_006230885, and others.
This siRNA also targets the following transcripts in Mouse: NM_001080390, NM_007928, NM_001080388, NM_001080389, AK172664, and others.

Matching Taqman Gene Expression Assay:

Hs00245216_m1

Gene Ontology Categories:

Process(es)

microtubule cytoskeleton organization
mitophagy
neuron migration
protein phosphorylation
positive regulation of neuron projection development
Wnt signaling pathway
peptidyl-threonine phosphorylation
establishment of cell polarity
activation of protein kinase activity
intracellular signal transduction
establishment or maintenance of epithelial cell apical/basal polarity
protein autophosphorylation
regulation of axonogenesis
regulation of cytoskeleton organization
mitochondrion localization
cell-cell adhesion

Function(s)

magnesium ion binding
protein serine/threonine kinase activity
protein binding
ATP binding
lipid binding
protein kinase activator activity
poly(A) RNA binding
tau-protein kinase activity
cadherin binding involved in cell-cell adhesion