s502587

• Gene Symbol: RPE65
• Gene Name: RPE65, retinoid isomerohydrolase
• Gene Aliases: BCO3, LCA2, RP20, mRPE65, rd12, sRPE65
• Chromosome Location: Chr.1: 68428822 - 68450322 on Build GRCh38
• UniGene ID: Hs.2133
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RPE65
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000329.2	NP_000320.1	6, 7	704
	XM_017002027.1	XP_016857516.1	5, 6	916
GenBank mRNA	AK289925.1	-	6, 7	695
	BC075035.2	-	6, 7	696	30915627
	BC075036.2	-	6, 7	699	30915421
	U18991.1	-	6, 7	704

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: BC090656, AF410461, BC130028, AK020906.

Gene Ontology Categories:

Process(es)

retinoid metabolic process
retina homeostasis
neural retina development
vitamin A metabolic process
regulation of rhodopsin gene expression
visual perception
circadian rhythm
insulin receptor signaling pathway
retinol metabolic process
retinal metabolic process
detection of light stimulus involved in visual perception
oxidation-reduction process
retina morphogenesis in camera-type eye
cellular response to electrical stimulus

Function(s)

phosphatidylserine binding
retinal isomerase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
phosphatidylcholine binding
metal ion binding
all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity
all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
cardiolipin binding