s529224

• Gene Symbol: NOS1
• Gene Name: nitric oxide synthase 1
• Gene Aliases: IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS
• Chromosome Location: Chr.12: 117208142 - 117441843 on Build GRCh38
• UniGene ID: Hs.654410
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NOS1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000620.4	NP_000611.1	7	2051
	NM_001204213.1	NP_001191142.1	6	643
	NM_001204214.1	NP_001191143.1	6	638
	NM_001204218.1	NP_001191147.1	7	2051
	XM_011538398.2	XP_011536700.1	8	1922
	XM_017019345.1	XP_016874834.1	7	2058
	XM_017019346.1	XP_016874835.1	7	1872
	XM_017019347.1	XP_016874836.1	7	1961
GenBank mRNA	AK294435.1	-	7	1855
	AK307481.1	-	7	2051
	D16408.1	-	6	1340
	EU753241.1	-	7	2025
	L02881.1	-	6	1767
	U17327.1	-	7	2025

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: X59949, U67309.

Gene Ontology Categories:

Process(es)

response to hypoxia
regulation of sodium ion transport
arginine catabolic process
nitric oxide biosynthetic process
striated muscle contraction
nitric oxide mediated signal transduction
myoblast fusion
female pregnancy
aging
negative regulation of cell proliferation
response to heat
response to lead ion
negative regulation of calcium ion transport into cytosol
response to activity
peptidyl-cysteine S-nitrosylation
positive regulation of guanylate cyclase activity
response to lipopolysaccharide
response to vitamin E
multicellular organismal response to stress
positive regulation of histone acetylation
response to nicotine
neurotransmitter biosynthetic process
exogenous drug catabolic process
negative regulation of apoptotic process
negative regulation of potassium ion transport
response to peptide hormone
response to estrogen
cell redox homeostasis
response to ethanol
negative regulation of blood pressure
negative regulation of heart contraction
positive regulation of transcription, DNA-templated
negative regulation of vasoconstriction
positive regulation of vasodilation
positive regulation of transcription from RNA polymerase II promoter
negative regulation of insulin secretion
behavioral response to cocaine
regulation of neurogenesis
negative regulation of hydrolase activity
negative regulation of cytosolic calcium ion concentration
negative regulation of serotonin uptake
negative regulation of calcium ion transport
regulation of sensory perception of pain
oxidation-reduction process
regulation of cardiac muscle contraction
regulation of ryanodine-sensitive calcium-release channel activity
cellular response to mechanical stimulus
cellular response to growth factor stimulus
response to nitric oxide
positive regulation of the force of heart contraction
positive regulation of long-term synaptic potentiation
negative regulation of adrenergic receptor signaling pathway involved in heart process
positive regulation of adrenergic receptor signaling pathway involved in heart process
positive regulation of neuron death
positive regulation of sodium ion transmembrane transport
regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
regulation of cardiac conduction

Function(s)

nitric-oxide synthase activity
iron ion binding
protein binding
calmodulin binding
FMN binding
sodium channel regulator activity
enzyme binding
heme binding
tetrahydrobiopterin binding
arginine binding
protein homodimerization activity
ion channel binding
cadmium ion binding
flavin adenine dinucleotide binding
NADP binding
scaffold protein binding