s530937

• Gene Symbol: TARDBP
• Gene Name: TAR DNA binding protein
• Gene Aliases: ALS10, TDP-43
• Chromosome Location: Chr.1: 11012622 - 11030528 on Build GRCh38
• UniGene ID: Hs.300624
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TARDBP
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007375.3	NP_031401.1	6	940
	XM_017000863.1	XP_016856352.1	6	928
	XM_017000864.1	XP_016856353.1	6	928
	XM_017000865.1	XP_016856354.1	6	928
	XM_017000866.1	XP_016856355.1	6	928
	XM_017000867.1	XP_016856356.1	6	928
	XM_017000868.1	XP_016856357.1	6	928
GenBank mRNA	AK222754.1	-	6	878
	AK295920.1	-	5	714
	AK299454.1	-	6	691
	AK312416.1	-	6	908
	AL050265.1	-	6	894
	BC001487.2	-	6	893
	BC071657.1	-	6	891	5498250
	BC095435.1	-	6	892	30389805
	CR533534.1	-	5	806
	EF434181.1	-	5	806
	EF434182.1	-	5	806
	EF434183.1	-	4	449
	HQ628633.1	-	4	642
	HQ628634.1	-	6	715
	HQ628635.1	-	5	806
	U23731.1	-	5	806

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: BC083752.
This siRNA also targets the following transcripts in Mouse: NR_027864, AK195880, GQ428777, BC012873, AK045495, and others.

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
transcription from RNA polymerase II promoter
mRNA processing
RNA splicing
negative regulation of gene expression
nuclear fragmentation involved in apoptotic nuclear change
positive regulation of insulin secretion
response to endoplasmic reticulum stress
negative regulation by host of viral transcription
positive regulation of transcription from RNA polymerase II promoter
regulation of cell cycle
3'-UTR-mediated mRNA stabilization
nuclear inner membrane organization

Function(s)

nucleotide binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
RNA binding
mRNA 3'-UTR binding
protein binding
identical protein binding
poly(A) RNA binding