s534383

• Gene Symbol: KCNH2
• Gene Name: potassium voltage-gated channel subfamily H member 2
• Gene Aliases: ERG-1, ERG1, H-ERG, HERG, HERG1, Kv11.1, LQT2, SQT1
• Chromosome Location: Chr.7: 150944956 - 150978314 on Build GRCh38
• UniGene ID: Hs.647099
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: KCNH2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001204798.1	NP_001191727.1	5	1956
	NM_172056.2	NP_742053.1	9	3051
GenBank mRNA	AB044806.1	-	9	2833
	AF052728.1	-	1	268
	AJ609614.1	-	5	1630
	AY927502.1	-	3	897
	BC001914.1	-	8	2307
	BT007336.1	-	8	2302

Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID	Transcript Location
GenBankmRNA	BM752339.1	-	1	246		Chr. 7 - 150949659 - 150950161 [-] on Build GRCh38
GenBankmRNA	R07383.1	-		223		Chr. - - [-] on Build
GenBankmRNA	AI630201.1	-	1	21		Chr. 7 - 150949569 - 150949929 [-] on Build GRCh38
GenBankmRNA	BM739789.1	-	1	266		Chr. 7 - 150949526 - 150950181 [-] on Build GRCh38
GenBankmRNA	BM739802.1	-	1	266		Chr. 7 - 150949673 - 150950181 [-] on Build GRCh38
GenBankmRNA	BM739001.1	-	1	266		Chr. 7 - 150949587 - 150950181 [-] on Build GRCh38
GenBankmRNA	DB566418.2	-	1	237		Chr. 7 - 150949427 - 150950153 [-] on Build GRCh38
GenBankmRNA	BM739833.1	-	1	266		Chr. 7 - 150949596 - 150950181 [-] on Build GRCh38
GenBankmRNA	BM726538.1	-	1	238		Chr. 7 - 150949502 - 150950153 [-] on Build GRCh38
GenBankmRNA	BM755683.1	-	1	248		Chr. 7 - 150949680 - 150950163 [-] on Build GRCh38
GenBankmRNA	BM754148.1	-	1	248		Chr. 7 - 150949693 - 150950163 [-] on Build GRCh38
GenBankmRNA	BQ068861.1	-	2	536		Chr. 7 - 150949625 - 150950951 [-] on Build GRCh38
GenBankmRNA	BQ787600.1	-	2	552		Chr. 7 - 150949867 - 150950967 [-] on Build GRCh38
GenBankmRNA	BM749663.1	-	1	266		Chr. 7 - 150949601 - 150950181 [-] on Build GRCh38
GenBankmRNA	BM770966.1	-	1	265		Chr. 7 - 150949689 - 150950181 [-] on Build GRCh38
GenBankmRNA	BM756495.1	-	1	266		Chr. 7 - 150949715 - 150950181 [-] on Build GRCh38

More Information

Gene Ontology Categories:

Process(es)

phosphorelay signal transduction system
regulation of heart rate by hormone
signal transduction by protein phosphorylation
cellular response to drug
regulation of membrane potential
potassium ion homeostasis
cardiac muscle contraction
regulation of membrane repolarization
regulation of ventricular cardiac muscle cell membrane repolarization
cardiac conduction
potassium ion export
potassium ion transmembrane transport
ventricular cardiac muscle cell action potential
membrane depolarization during action potential
membrane repolarization during action potential
membrane repolarization during cardiac muscle cell action potential
regulation of heart rate by cardiac conduction
potassium ion export across plasma membrane
membrane repolarization during ventricular cardiac muscle cell action potential
regulation of potassium ion transmembrane transport
negative regulation of potassium ion transmembrane transport
positive regulation of potassium ion transmembrane transport
negative regulation of potassium ion export

Function(s)

phosphorelay sensor kinase activity
inward rectifier potassium channel activity
voltage-gated potassium channel activity
delayed rectifier potassium channel activity
protein binding
ubiquitin protein ligase binding
identical protein binding
protein homodimerization activity
C3HC4-type RING finger domain binding
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
scaffold protein binding
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization