s536427

• Gene Symbol: CYLD
• Gene Name: CYLD lysine 63 deubiquitinase
• Gene Aliases: BRSS, CDMT, CYLD1, CYLDI, EAC, MFT, MFT1, SBS, TEM, USPL2
• Chromosome Location: Chr.16: 50742026 - 50801935 on Build GRCh38
• UniGene ID: Hs.578973
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CYLD
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001042355.1	NP_001035814.1	18	5877
	NM_001042412.1	NP_001035877.1	18	5901
	NM_015247.2	NP_056062.1	20	6023
	XM_005255812.2	XP_005255869.1	19	5974
	XM_006721149.1	XP_006721212.1	19	6038
	XM_011522907.2	XP_011521209.1	18	5800
	XM_011522908.1	XP_011521210.1	18	5862
	XM_017022977.1	XP_016878466.1	18	6172
	XM_017022978.1	XP_016878467.1	18	5968
	XM_017022979.1	XP_016878468.1	18	5928
	XM_017022980.1	XP_016878469.1	18	5961
	XM_017022981.1	XP_016878470.1	18	5829
GenBank mRNA	DA940312.1	-	1	245

More Information

Gene Ontology Categories:

Process(es)

ubiquitin-dependent protein catabolic process
cell cycle
regulation of mitotic cell cycle
regulation of tumor necrosis factor-mediated signaling pathway
Wnt signaling pathway
negative regulation of NF-kappaB transcription factor activity
negative regulation of type I interferon production
negative regulation of NF-kappaB import into nucleus
negative regulation of T cell differentiation
necroptotic process
nucleotide-binding oligomerization domain containing signaling pathway
regulation of microtubule cytoskeleton organization
protein K63-linked deubiquitination
negative regulation of canonical Wnt signaling pathway
ripoptosome assembly involved in necroptotic process
regulation of cilium assembly
positive regulation of extrinsic apoptotic signaling pathway
regulation of intrinsic apoptotic signaling pathway

Function(s)

thiol-dependent ubiquitin-specific protease activity
protein binding
zinc ion binding
protein kinase binding
Lys63-specific deubiquitinase activity
proline-rich region binding