s62145

• Gene Symbol: Agtr1a
• Gene Name: angiotensin II receptor, type 1a
• Gene Aliases: 1810074K20Rik, AG2S, AI551199, AT1, AT1a, AT2R1, AT2R1A, Agtr-1a, Agtr1, Angtr-1a
• Chromosome Location: Chr.13: 30336356 - 30382867 on Build GRCm38
• UniGene ID: Mm.35062
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Agtr1a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_177322.3	NP_796296.1	3	598
GenBank mRNA	BC036175.1	-	3	497	4989471

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_030985, XM_008771594, XM_006253882, XM_008771593, BC078810, and others.

• Set Membership: G-protein coupled receptor

Gene Ontology Categories:

Process(es)

blood vessel development
kidney development
positive regulation of receptor recycling
regulation of systemic arterial blood pressure by circulatory renin-angiotensin
renin secretion into blood stream
renin-angiotensin regulation of aldosterone production
regulation of renal output by angiotensin
brain renin-angiotensin system
regulation of pH
inflammatory response
signal transduction
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
Rho protein signal transduction
heart development
positive regulation of cell proliferation
positive regulation of cholesterol esterification
regulation of vasoconstriction
calcium-mediated signaling
positive regulation of cellular protein metabolic process
positive regulation of phospholipase A2 activity
positive regulation of superoxide anion generation
regulation of smooth muscle cell apoptotic process
negative regulation of smooth muscle cell apoptotic process
angiotensin-activated signaling pathway
vasoconstriction
dopamine biosynthetic process
drinking behavior
activation of Janus kinase activity
negative regulation of neuron apoptotic process
response to estrogen
positive regulation of blood pressure
positive regulation of cytokine secretion
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
cell chemotaxis
cellular response to dexamethasone stimulus
phospholipase C-activating angiotensin-activated signaling pathway
positive regulation of branching involved in ureteric bud morphogenesis

Function(s)

angiotensin type I receptor activity
G-protein alpha-subunit binding
signal transducer activity
G-protein coupled receptor activity
angiotensin type II receptor activity
protein binding
peptide hormone binding
protein kinase binding
bradykinin receptor binding
D1 dopamine receptor binding
protein self-association
protein heterodimerization activity