s6611

Gene Symbol:

HLA-DRB4 HLA-DRB1 HLA-DRB3 HLA-DRB5 LOC105369230

Gene Name:

major histocompatibility complex, class II, DR beta 4

major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 3

major histocompatibility complex, class II, DR beta 5

HLA class II histocompatibility antigen, DRB1-7 beta chain

Gene Aliases:

DR-4, DR4, DRB4, HLA-DR4B

DRB1, DRw10, HLA-DR1B, HLA-DRB, SS1

DRB1, DRw10, HLA-DR1B, HLA-DR3B, HLA-DRB, SS1

HLA-DRB

HLA-DRB1

Chromosome Location:

-

Chromosome Location:

Chr.6: 32578769 - 32589836 on Build GRCh38

Chromosome Location:

-

Chromosome Location:

Chr.6: 32517343 - 32530316 on Build GRCh38

Chromosome Location:

-

UniGene ID:

Hs.534322

Hs.534322

Hs.696211

Hs.485130

Hs.696211

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

-

-

siRNA Details

Gene Symbol: HLA-DRB4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_021983.4	NP_068818.4	4	737
GenBank mRNA	AF048707.1	-	3	527
	AF361548.1	-	5	675
	AF361549.1	-	5	675
	AK225683.1	-	4	729
	AK225690.1	-	4	729
	AK291499.1	-	4	729
	AK292151.1	-	5	717
	AK293020.1	-	4	770
	AY961064.1	-	4	666
	AY961067.1	-	4	666
	AY961070.2	-	4	666
	BC005312.1	-	5	729	3933019
	DQ284431.1	-	4	727
	DQ284433.1	-	4	728
	GQ891550.1	-	4	666
	M15178.1	-	5	608
	M16942.1	-	5	694
	M17385.1	-	3	579

Gene Symbol: HLA-DRB1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001243965.1	NP_001230894.1	4	760
	NM_002124.3	NP_002115.2	4	760
GenBank mRNA	AF291675.1	-	4	666
	AJ297583.1	-	4	666
	AJ297585.1	-	4	666
	AJ297586.2	-	4	666
	AJ297587.1	-	4	666
	AJ697892.1	-	4	675
	AJ697893.1	-	4	675
	AK289463.1	-	4	729
	AK291987.1	-	4	760
	AY626551.1	-	4	666
	AY770514.1	-	4	666
	AY935719.1	-	4	666
	AY961062.1	-	4	666
	AY961063.1	-	4	666
	AY961065.1	-	4	666
	AY961066.1	-	4	666
	AY961068.1	-	4	666
	AY961072.1	-	4	666
	AY961073.1	-	4	666
	AY961076.1	-	4	666
	AY961077.1	-	4	666
	AY961078.1	-	4	666
	BC007920.2	-	4	712	4309837
	BC008403.1	-	4	729	4272571
	BC024269.1	-	4	709	4852401
	BC031023.1	-	4	729	4695321
	BC033827.1	-	4	709	5216243
	BC108922.1	-	4	721	40023604
	DQ002917.1	-	4	666
	DQ090958.1	-	4	666
	DQ140279.1	-	4	726
	HG974574.1	-	4	666
	HG974596.1	-	4	666
	HG974600.1	-	4	666
	HM067861.1	-	4	666
	HM067862.1	-	4	666
	HM067863.1	-	4	666
	KJ534866.1	-	4	666
	L02545.1	-	4	680
	L42143.1	-	4	666
	L76133.1	-	4	706
	M11161.1	-	4	666
	M11867.1	-	4	695
	M14661.1	-	3	528
	M14662.1	-	3	579
	M16957.1	-	3	579
	M16959.1	-	3	579
	M17378.1	-	3	579
	M17381.1	-	3	579
	M17384.1	-	3	579
	M20138.1	-	4	668
	M20430.1	-	4	709
	M20504.1	-	5	701
	M21008.1	-	3	559
	M26038.1	-	4	712
	M27635.1	-	4	703
	M28583.1	-	5	705
	M28584.1	-	4	637
	M33600.1	-	4	736
	U56640.1	-	3	523
	U65585.1	-	4	706
	U95817.1	-	3	579
	X00699.1	-	4	701
	X00700.1	-	4	670
X02902.1	-	4	722
X03069.1	-	4	728

Gene Symbol: HLA-DRB3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_022555.3	NP_072049.2	4	706
GenBank mRNA	A06800.1	-	4	702
	AF000448.1	-	4	579
	AF192258.1	-	3	579
	AF192259.1	-	3	579
	AF199236.2	-	5	687
	AK226043.1	-	4	732
	AY138123.1	-	4	666
	BC001023.2	-	4	726	3345335
	BC008987.1	-	4	690	4184806
	BC106057.1	-	4	769	4385464
	KJ534865.1	-	4	666
	M16941.1	-	4	689
	M17380.1	-	3	579
	M28991.1	-	4	624
	M28992.1	-	4	585
	U66825.1	-	4	706
	U95819.1	-	4	680
	V00522.1	-	4	701

Gene Symbol: HLA-DRB5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AB062112.2	-	4	710
	AF490771.1	-	4	647
	AJ297582.1	-	4	666
	AK292140.1	-	4	729
	M17379.1	-	3	579
	M17382.1	-	3	579
	M17383.1	-	3	579
	M27689.1	-	3	579
	U66826.1	-	4	706
	X99895.1	-	4	673

Gene Symbol: LOC105369230
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	HG974601.1	-	4	666
	HM067848.1	-	4	666

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

antigen processing and presentation of exogenous peptide antigen via MHC class II
T cell costimulation
T cell receptor signaling pathway
interferon-gamma-mediated signaling pathway
polysaccharide assembly with MHC class II protein complex
signal transduction

Function(s)

MHC class II protein complex binding
peptide antigen binding
MHC class II receptor activity