s6625

• Gene Symbol: HLA-E
• Gene Name: major histocompatibility complex, class I, E
• Gene Aliases: EA1.2, EA2.1, HLA-6.2, MHC, QA1
• Chromosome Location: Chr.6: 30489406 - 30494205 on Build GRCh38
• UniGene ID: Hs.650174
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HLA-E
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005516.5	NP_005507.3	2	408
	XM_017010807.1	XP_016866296.1	1	420
	XM_017010808.1	XP_016866297.1	1	420
	XM_017010809.1	XP_016866298.1	2	305
GenBank mRNA	AB209870.1	-	2	275
	AJ293263.1	-	2	282
	AJ293264.1	-	2	282
	AK098434.1	-	2	305
	AK225048.1	-	2	302
	AK292391.1	-	2	360
	AK296822.1	-	1	432
	AK298695.1	-	2	302
	AK300906.1	-	2	302
	AK314411.1	-	2	302
	AK316327.1	-	2	307
	AY216681.1	-	2	282
	AY221103.1	-	2	282
	BC002578.2	-	2	296	3140835
	BC004297.1	-	2	280
	BC040479.1	-	2	302	4696327
	BM791769.1	-	2	347
	BX538084.1	-	1	200
	DA832616.1	-	2	408
	L78455.1	-	1	219
	L78934.1	-	1	218
	M20022.1	-	2	289
	M31183.1	-	2	254

More Information

Gene Ontology Categories:

Process(es)

positive regulation of T cell mediated cytotoxicity
adaptive immune response
antigen processing and presentation of peptide antigen via MHC class I
antigen processing and presentation of endogenous peptide antigen via MHC class Ib
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
regulation of natural killer cell mediated immunity
positive regulation of natural killer cell mediated immunity
antibacterial humoral response
positive regulation of interleukin-13 production
positive regulation of interleukin-4 production
positive regulation of TRAIL production
positive regulation of tumor necrosis factor production
CD8-positive, alpha-beta T cell activation
protection from natural killer cell mediated cytotoxicity
innate immune response
regulation of immune response
defense response to Gram-positive bacterium
positive regulation of immunoglobulin secretion
interferon-gamma-mediated signaling pathway
type I interferon signaling pathway
positive regulation of CD8-positive, alpha-beta T cell proliferation

Function(s)

receptor binding
beta-2-microglobulin binding
MHC class I protein binding
peptide antigen binding
natural killer cell lectin-like receptor binding