s67489

• Gene Symbol: Hfe
• Gene Name: hemochromatosis
• Gene Aliases: MR2
• Chromosome Location: Chr.13: 23703564 - 23710986 on Build GRCm38
• UniGene ID: Mm.2681
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Hfe
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010424.4	NP_034554.2	2	428
GenBank mRNA	AK009581.1	-	2	429
	AK088986.1	-	2	424
	AK150697.1	-	2	446
	BC116744.1	-	2	386	40126063
	BC116746.1	-	2	384	40126065
	U66849.1	-	2	410

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053301, AJ001517, AF008587.

Gene Ontology Categories:

Process(es)

immune system process
antigen processing and presentation of peptide antigen via MHC class I
immune response
positive regulation of gene expression
positive regulation of pathway-restricted SMAD protein phosphorylation
antigen processing and presentation
BMP signaling pathway
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
hormone biosynthetic process
iron ion homeostasis
multicellular organismal iron ion homeostasis
iron ion import into cell
negative regulation of receptor binding
negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Function(s)

antigen binding
receptor binding
co-receptor binding
peptide antigen binding
transferrin receptor binding