s69763

• Gene Symbol: Mecp2
• Gene Name: methyl CpG binding protein 2
• Gene Aliases: 1500041B07Rik, D630021H01Rik, Mbd5, WBP10
• Chromosome Location: Chr.X: 74026592 - 74085690 on Build GRCm38
• UniGene ID: Mm.131408
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Mecp2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001081979.2	NP_001075448.1	3	623
	NM_010788.4	NP_034918.1	4	747
GenBank mRNA	AB221662.1	-	3	468
	AF072251.1	-	3	468
	AF158181.1	-	4	650
	AJ132922.1	-	3	503
	AK158664.1	-	3	570
	BC027153.1	-	4	669	4948925

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001110792, NM_004992, AK289444, HQ141378, GU812286, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
behavioral fear response
response to hypoxia
startle response
neurological system process involved in regulation of systemic arterial blood pressure
regulation of respiratory gaseous exchange by neurological system process
inositol metabolic process
mitochondrial electron transport, ubiquinol to cytochrome c
chromatin silencing
regulation of gene expression by genetic imprinting
transcription, DNA-templated
regulation of transcription, DNA-templated
glutamine metabolic process
cellular biogenic amine metabolic process
chemical synaptic transmission
synapse assembly
brain development
respiratory gaseous exchange
learning
memory
long-term memory
protein localization
glucocorticoid metabolic process
positive regulation of cell proliferation
adult locomotory behavior
visual learning
pathogenesis
embryo development
post-embryonic development
regulation of gene expression
dendrite development
histone methylation
histone acetylation
proprioception
sensory perception of pain
cerebellum development
ventricular system development
neuron differentiation
negative regulation of histone methylation
neuron projection development
cardiolipin metabolic process
multicellular organismal response to stress
negative regulation of histone acetylation
social behavior
regulation of gene expression, epigenetic
neuron maturation
negative regulation of neuron apoptotic process
regulation of DNA methylation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
phosphatidylcholine metabolic process
regulation of synaptic plasticity
negative regulation of astrocyte differentiation
catecholamine secretion
neuromuscular process controlling posture
neuromuscular process
positive regulation of synapse assembly
excitatory postsynaptic potential
long-term synaptic potentiation

Function(s)

four-way junction DNA binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
mRNA binding
protein binding
transcription factor binding
methyl-CpG binding
double-stranded methylated DNA binding
enzyme binding
protein domain specific binding
chromatin DNA binding
siRNA binding
histone deacetylase binding
poly(A) RNA binding
unmethylated CpG binding
protein N-terminus binding