s7044

• Gene Symbol: HTR2B
• Gene Name: 5-hydroxytryptamine receptor 2B
• Gene Aliases: 5-HT(2B), 5-HT-2B, 5-HT2B
• Chromosome Location: Chr.2: 231108230 - 231125778 on Build GRCh38
• UniGene ID: Hs.421649
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HTR2B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000867.4	NP_000858.3	4	1854
	NM_001320758.1	NP_001307687.1	4	1471
	XM_005246520.3	XP_005246577.1	3	1804
	XM_006712482.2	XP_006712545.1	4	2051
GenBank mRNA	AK313741.1	-	4	1786
	AY136751.1	-	3	1349
	BC063123.1	-	4	1858	30321290
	X77307.1	-	3	1404

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_017250, XM_008767216, X66842.
This siRNA also targets the following transcripts in Mouse: NM_008311, BC023690, AK033713, AF498255, AF498254.

• Set Membership: G-protein coupled receptor

Gene Ontology Categories:

Process(es)

neural crest cell migration
positive regulation of cytokine production
positive regulation of endothelial cell proliferation
G-protein coupled receptor internalization
heart morphogenesis
cardiac muscle hypertrophy
cGMP biosynthetic process
cellular calcium ion homeostasis
G-protein coupled receptor signaling pathway
activation of phospholipase C activity
protein kinase C-activating G-protein coupled receptor signaling pathway
serotonin receptor signaling pathway
behavior
positive regulation of cell proliferation
negative regulation of autophagy
positive regulation of phosphatidylinositol biosynthetic process
neural crest cell differentiation
phosphatidylinositol 3-kinase signaling
intestine smooth muscle contraction
phosphorylation
calcium-mediated signaling
hepatic stellate cell activation
vasoconstriction
response to drug
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of MAP kinase activity
positive regulation of GTPase activity
inositol phosphate metabolic process
embryonic morphogenesis
positive regulation of cytokine secretion
regulation of behavior
positive regulation of nitric-oxide synthase activity
release of sequestered calcium ion into cytosol
positive regulation of cell division
negative regulation of cell death
ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
protein kinase C signaling
cellular response to amine stimulus
cellular response to temperature stimulus
cellular response to serotonin

Function(s)

G-protein alpha-subunit binding
G-protein coupled serotonin receptor activity
GTPase activator activity
drug binding
serotonin binding