s70694

• Gene Symbol: Nos2
• Gene Name: nitric oxide synthase 2, inducible
• Gene Aliases: NOS-II, Nos-2, Nos2a, i-NOS, iNOS
• Chromosome Location: Chr.11: 78920859 - 78960232 on Build GRCm38
• UniGene ID: Mm.2893
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nos2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010927.3	NP_035057.1	14	1792
GenBank mRNA	AF065919.1	-	14	1789
	AF065920.1	-	14	1789
	AF065921.2	-	14	1789
	AF065922.2	-	13	1662
	AF065923.2	-	13	1662
	AY090567.1	-	13	1612
	BC062378.1	-	14	1801	4978648
	M84373.1	-	14	1793
	M87039.1	-	14	1864
	M92649.1	-	14	1800
	U43428.1	-	14	1680

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012611, XM_008768231, XM_008768232, XM_006246949, AF006619, and others.

Gene Ontology Categories:

Process(es)

ovulation from ovarian follicle
response to hypoxia
arginine catabolic process
superoxide metabolic process
nitric oxide biosynthetic process
inflammatory response
nitric oxide mediated signal transduction
negative regulation of gene expression
peptidyl-cysteine S-nitrosylation
positive regulation of guanylate cyclase activity
response to lipopolysaccharide
cellular response to drug
regulation of cell proliferation
negative regulation of protein catabolic process
defense response to bacterium
negative regulation of blood pressure
regulation of protein kinase activity
positive regulation of vasodilation
regulation of insulin secretion
positive regulation of killing of cells of other organism
oxidation-reduction process
cellular response to lipopolysaccharide
cellular response to interferon-gamma

Function(s)

actin binding
NADPH-hemoprotein reductase activity
nitric-oxide synthase activity
receptor binding
iron ion binding
protein binding
calmodulin binding
beta-catenin binding
cAMP-dependent protein kinase regulator activity
FMN binding
oxidoreductase activity
protein kinase binding
heme binding
tetrahydrobiopterin binding
arginine binding
protein homodimerization activity
cadherin binding
metal ion binding
flavin adenine dinucleotide binding
nitric-oxide synthase binding
Hsp90 protein binding