s72732

• Gene Symbol: Rara
• Gene Name: retinoic acid receptor, alpha
• Gene Aliases: Nr1b1, RAR, RARalpha1
• Chromosome Location: Chr.11: 98927809 - 98974942 on Build GRCm38
• UniGene ID: Mm.439744
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Rara
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001177302.1	NP_001170773.1	3	743
	NM_001177303.1	NP_001170774.1	2	488
	NM_009024.2	NP_033050.2	2	610
GenBank mRNA	AB221572.1	-	1	57
	AK042163.1	-	2	489
	AK154623.1	-	2	583
	BC010216.1	-	2	608	3498142
	BC040383.1	-	3	743
	BC090396.1	-	1	154
	CT010231.1	-	1	53
	S56656.1	-	2	590
	X56572.1	-	2	631

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_008767945.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
ureteric bud development
neural tube closure
glandular epithelial cell development
outflow tract septum morphogenesis
growth plate cartilage development
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein phosphorylation
signal transduction
germ cell development
spermatogenesis
positive regulation of cell proliferation
negative regulation of cell proliferation
male gonad development
positive regulation of gene expression
negative regulation of gene expression
positive regulation of phosphatidylinositol 3-kinase signaling
negative regulation of translation
regulation of granulocyte differentiation
negative regulation of granulocyte differentiation
embryonic camera-type eye development
regulation of myelination
response to retinoic acid
negative regulation of interferon-gamma production
negative regulation of tumor necrosis factor production
positive regulation of interleukin-13 production
positive regulation of interleukin-4 production
positive regulation of interleukin-5 production
multicellular organism growth
regulation of apoptotic process
negative regulation of apoptotic process
apoptotic cell clearance
steroid hormone mediated signaling pathway
regulation of phosphatidylinositol 3-kinase activity
response to ethanol
negative regulation of cell differentiation
positive regulation of T-helper 2 cell differentiation
positive regulation of neuron differentiation
positive regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of translational initiation
regulation of synaptic plasticity
retinoic acid receptor signaling pathway
positive regulation of binding
positive regulation of protein kinase B signaling
ventricular cardiac muscle cell differentiation
Sertoli cell fate commitment
limb development
face development
bone development
trachea cartilage development
chondroblast differentiation
negative regulation of cartilage development
positive regulation of ERK1 and ERK2 cascade
cellular response to lipopolysaccharide
cellular response to retinoic acid
cellular response to estrogen stimulus

Function(s)

translation repressor activity, nucleic acid binding
regulatory region DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region DNA binding
retinoic acid binding
DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
retinoic acid receptor activity
transcription coactivator activity
transcription corepressor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
receptor binding
protein binding
transcription factor binding
drug binding
zinc ion binding
enzyme binding
protein domain specific binding
chromatin DNA binding
phosphatidylinositol 3-kinase regulator activity
histone deacetylase binding
protein kinase B binding
sequence-specific DNA binding
transcription regulatory region DNA binding
retinoic acid-responsive element binding
metal ion binding
protein heterodimerization activity
mRNA 5'-UTR binding
protein kinase A binding
alpha-actinin binding