s75188

• Gene Symbol: Tle1
• Gene Name: transducin-like enhancer of split 1, homolog of Drosophila E(spl)
• Gene Aliases: C230057C06Rik, Estm14, Grg-1, Grg1, Tle4l
• Chromosome Location: Chr.4: 72109945 - 72200893 on Build GRCm38
• UniGene ID: Mm.278444
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tle1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001285529.1	NP_001272458.1	11	1694
	NM_001285530.1	NP_001272459.1	9	1475
	NM_011599.5	NP_035729.3	11	1697
GenBank mRNA	AK048515.1	-	11	1684
	AK052961.1	-	9	1798
	AK082499.1	-	11	1663
	AY155195.1	-	11	856
	AY155197.1	-	9	633
	AY155198.1	-	7	496
	AY155199.1	-	11	856
	AY155200.1	-	5	330
	BC057573.1	-	11	1524	6401650
	U61362.1	-	11	863

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001173433, XM_008763792, XM_008763793, XM_006238281, XM_008763789, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
positive regulation of gene expression
Wnt signaling pathway
negative regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of transcription, DNA-templated
negative regulation of anoikis

Function(s)

RNA polymerase II transcription corepressor activity
chromatin binding
transcription corepressor activity
protein binding
transcription factor binding
identical protein binding