s75190

• Gene Symbol: Tle1
• Gene Name: transducin-like enhancer of split 1, homolog of Drosophila E(spl)
• Gene Aliases: C230057C06Rik, Estm14, Grg-1, Grg1, Tle4l
• Chromosome Location: Chr.4: 72109945 - 72200893 on Build GRCm38
• UniGene ID: Mm.278444
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tle1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001285529.1	NP_001272458.1	4	1092
	NM_001285530.1	NP_001272459.1	4	1092
	NM_001285531.1	NP_001272460.1	4	1092
	NM_001285532.1	NP_001272461.1	4	1092
	NM_011599.5	NP_035729.3	4	1092
GenBank mRNA	AK044642.1	-	4	1094
	AK046402.1	-	4	1060
	AK048515.1	-	4	1078
	AK052961.1	-	2	1193
	AK076750.1	-	4	474
	AK082499.1	-	4	1058
	AY155195.1	-	4	251
	AY155196.1	-	4	1061
	AY155197.1	-	4	250
	AY155198.1	-	4	251
	AY155199.1	-	4	251
	BC057573.1	-	4	922	6401650
	U61362.1	-	4	258

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_005077, AK293606, AK290860, BC010100, BC015747, and others.
This siRNA also targets the following transcripts in Rat: NM_001173433, XM_006238281, XM_008763789, XM_008763788, XM_006238284, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
positive regulation of gene expression
Wnt signaling pathway
negative regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of transcription, DNA-templated
negative regulation of anoikis

Function(s)

RNA polymerase II transcription corepressor activity
chromatin binding
transcription corepressor activity
protein binding
transcription factor binding
identical protein binding