s758 Validated

• Gene Symbol: RHOA
• Gene Name: ras homolog family member A
• Gene Aliases: ARH12, ARHA, RHO12, RHOH12
• Chromosome Location: Chr.3: 49359136 - 49412097 on Build GRCh38
• UniGene ID: Hs.247077
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RHOA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001313941.1	NP_001300870.1	3	491
	NM_001313943.1	NP_001300872.1	2	396
	NM_001313944.1	NP_001300873.1	2	396
	NM_001313945.1	NP_001300874.1	2	273
	NM_001313946.1	NP_001300875.1	2	396
	NM_001313947.1	NP_001300876.1	2	396
	NM_001664.3	NP_001655.1	2	396
GenBank mRNA	AF498970.1	-	1	116
	AK130066.1	-	2	392
	AK130808.1	-	2	272
	AK222556.1	-	2	288
	AK296654.1	-	2	272
	AK307220.1	-	2	171
	AW403464.1	-	2	273
	BC001360.2	-	2	228	3051460
	BC005976.1	-	2	233	4102976
	BF966305.1	-	3	366
	BQ721697.1	-	2	269
	BT019870.1	-	1	116
	BU509012.1	-	2	227
	BX647063.1	-	2	292
	L09159.1	-	1	105
	L25080.1	-	2	267
	LN607834.1	-	1	94
	X05026.1	-	2	274

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_182670, CK603687, BC083656, AY149343.

Matching Taqman Gene Expression Assay:

Hs00357608_m1

Gene Ontology Categories:

Process(es)

transforming growth factor beta receptor signaling pathway
Rho protein signal transduction
viral process
cell migration
substantia nigra development
actin cytoskeleton organization
platelet activation
regulation of cell migration
actin cytoskeleton reorganization
positive regulation of cytokinesis
regulation of actin cytoskeleton organization
regulation of osteoblast proliferation
Roundabout signaling pathway
cleavage furrow formation
apolipoprotein A-I-mediated signaling pathway
positive regulation of NF-kappaB import into nucleus
positive regulation of I-kappaB kinase/NF-kappaB signaling
stress fiber assembly
apical junction assembly
endothelial cell migration
ossification involved in bone maturation
wound healing, spreading of cells
positive regulation of neuron differentiation
vascular endothelial growth factor receptor signaling pathway
ephrin receptor signaling pathway
phosphatidylinositol-mediated signaling
negative regulation of axonogenesis
positive regulation of axonogenesis
negative chemotaxis
regulation of small GTPase mediated signal transduction
positive regulation of stress fiber assembly
Wnt signaling pathway, planar cell polarity pathway
positive regulation of lipase activity
trabecula morphogenesis
positive regulation of protein serine/threonine kinase activity
negative regulation of cell migration involved in sprouting angiogenesis
mitotic spindle assembly
endothelial tube lumen extension
skeletal muscle satellite cell migration
mitotic cleavage furrow formation
regulation of cell motility

Function(s)

GTPase activity
protein binding
GTP binding
myosin binding