s8629

• Gene Symbol: MDM2
• Gene Name: MDM2 proto-oncogene
• Gene Aliases: ACTFS, HDMX, hdm2
• Chromosome Location: Chr.12: 68808149 - 68845544 on Build GRCh38
• UniGene ID: Hs.484551
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MDM2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001145337.2	NP_001138809.1	3, 4	228
	NM_001145339.2	NP_001138811.1	3, 4	478
	NM_002392.5	NP_002383.2	3, 4	478
	XM_005268872.4	XP_005268929.1	3, 4	406
GenBank mRNA	AF092843.1	-	3, 4	186
	AF092844.1	-	3, 4	186
	AF385323.1	-	2, 3	154
	AF385324.1	-	2, 3	154
	AF385326.1	-	2, 3	154
	AJ430612.1	-	2, 3	154
	AJ430614.1	-	2, 3	154
	AJ491698.1	-	2, 3	154
	AJ491700.1	-	2, 3	154
	AJ550518.1	-	2, 3	154
	AJ550519.1	-	2, 3	154
	AK290341.1	-	3, 4	428
	AM902646.1	-	2, 3	154
	AM902650.1	-	2, 3	154
	AM902651.1	-	2, 3	154
	AM902654.1	-	2, 3	154
	AM902655.1	-	2, 3	154
	AM902659.1	-	2, 3	154
	AM902660.1	-	2, 3	154
	AM902666.1	-	2, 3	154
	AM902667.1	-	2, 3	154
	AM902668.1	-	2, 3	154
	AM902669.1	-	2, 3	154
	AM902672.1	-	2, 3	154
	AM902678.1	-	2, 3	154
	AM902680.1	-	2, 3	154
	AM902681.1	-	2, 3	154
	BC152384.1	-	2, 3	157
	BC152390.1	-	2, 3	157
	BE296905.1	-	3, 4	443
	BT007258.1	-	2, 3	154
	EU076747.1	-	3, 4	228
	EU076749.1	-	3, 4	228
	HM213901.1	-	2, 3	154
	HY174841.1	-		480
	JX015379.1	-	2, 3	154
	JX015380.1	-	2, 3	154
	JX015387.1	-	2, 3	154
	JX015389.1	-	2, 3	154
	JX015390.1	-	2, 3	154
	JX015392.1	-	2, 3	154
	M92424.1	-	3, 4	465
	U33203.1	-	2, 3	154
	Z12020.1	-	3, 4	465

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
blood vessel development
blood vessel remodeling
regulation of heart rate
atrioventricular valve morphogenesis
endocardial cushion morphogenesis
ventricular septum development
atrial septum development
protein complex assembly
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
traversing start control point of mitotic cell cycle
positive regulation of cell proliferation
response to toxic substance
response to carbohydrate
response to iron ion
positive regulation of gene expression
negative regulation of protein processing
viral process
protein ubiquitination
protein sumoylation
peptidyl-lysine modification
protein destabilization
response to magnesium ion
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein localization to nucleus
regulation of protein catabolic process
response to cocaine
response to drug
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
response to morphine
negative regulation of DNA damage response, signal transduction by p53 class mediator
establishment of protein localization
response to ether
negative regulation of transcription, DNA-templated
positive regulation of mitotic cell cycle
response to antibiotic
positive regulation of protein export from nucleus
response to steroid hormone
cardiac septum morphogenesis
cellular response to hydrogen peroxide
negative regulation of cell cycle arrest
cellular response to antibiotic
cellular response to vitamin B1
cellular response to alkaloid
cellular response to growth factor stimulus
cellular response to peptide hormone stimulus
cellular response to estrogen stimulus
cellular response to hypoxia
cellular response to UV-C
regulation of signal transduction by p53 class mediator
negative regulation of signal transduction by p53 class mediator

Function(s)

p53 binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
SUMO transferase activity
enzyme binding
ubiquitin protein ligase binding
identical protein binding
peroxisome proliferator activated receptor binding
ubiquitin protein ligase activity
scaffold protein binding