1,1-Dimethylbiguanide Hydrochloride, MP Biomedicals™

1,1-Dimethylbiguanide Hydrochloride, White Powder

• It has various medical uses such as in polycystic ovary syndrome, non-alcoholic fatty liver disease and diabetes mellitus type 2.
• It may also reduce weight gain in people taking atypical antipsychotics. 1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels.
• 1,1-Dimethylbiguanide, Hydrochloride (Metformin) is a biguanide antihyperglycemic agent. 1,1-Dimethylbiguanide hydrochloride (metformin) is a strong base.
• It forms well defined salts and possessing excellent coordination capacity with transition metals, forming highly colored bidentate chelate complexes.
• Metformin (MET) exists in various forms: diprotonated (H2MET)2+ in strong acidic solution, monoprotonated (HMET)+ in weak acid, MET in neutral and deprotonated (MET)- in strong alkali solution. It is an oral antidiabetic drug.
• Pharmacokinetics of metformin has been studied. Determination of metformin in human plasma has been described by simple HPLC-UV method.[5] Metformin is reported to increase plasma active glucagon-like peptide-1 (GLP-1) in humans

Chemical Identifiers

CAS

1115-70-4

Molecular Formula

C4H12ClN5

Molecular Weight (g/mol)

165.63

MDL Number

MFCD00012582

InChI Key

OETHQSJEHLVLGH-UHFFFAOYSA-N

Synonym

N,N-Dimethylimidodicarbonimidic diamine, 1,1-Dimethylbiguanide hydrochloride, DMGG, LA-6023

IUPAC Name

hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride

SMILES

[H+].[Cl-].CN(C)C(=N)N=C(N)N

Color

White

Melting Point

214°C to 224°C

Quantity

25g

Solubility Information

Soluble in water (100mg/mL - clear, colorless solution), 95% ethanol; insoluble in ether, acetone or chloroform.

Physical Form

Powder

RTECSNumber

DU1800000

storageNote1

Store at Room Temperature (15-30°C).

RTECSNumber

DU1800000

storageNote1

Store at Room Temperature (15-30°C).