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2-Cl-IB-MECA, Tocris Bioscience™

Catalog No. p-4783162 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Highly selective A3 agonist

High affinity and extremely selective A3 adenosine receptor agonist (Ki = 0.33 nM). Displays 2500- and 1400-fold selectivity over A1 and A2A receptors respectively. Exhibits high selectivity over the Na+-independent adenosine transporter.

Chemical Identifiers

CAS 163042-96-4
Molecular Formula C18H18ClIN6O4
Molecular Weight (g/mol) 544.734
InChI Key IPSYPUKKXMNCNQ-PFHKOEEOSA-N
Synonym 2-cl-ib-meca, cl-ib-meca, c-ibza-mu, namodenoson, ci-ib-meca, 2s,3s,4r,5r-5-2-chloro-6-3-iodobenzyl amino-9h-purin-9-yl-3,4-dihydroxy-n-methyltetrahydrofuran-2-carboxamide, unii-z07jr07j6c, 2cl-ib-meca, 2-chloro-n 6-3-iodobenzyl adenosine-5'-n-methyluronamide, 1-2-chloro-6-3-iodophenyl methyl amino-9h-purin-9-yl-1-deoxy-n-methyl-beta-d-ribofuranuronamide
PubChem CID 3035850
IUPAC Name (2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide
SMILES CNC(=O)C1C(C(C(O1)N2C=NC3=C2N=C(N=C3NCC4=CC(=CC=C4)I)Cl)O)O

Specifications

Quantity 10 mg
Formula Weight 544.74
Percent Purity >98%
Chemical Name or Material 2-Cl-IB-MECA

Safety and Handling

Recommended Storage Desiccate at +4°C
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