Thermo Scientific Chemicals 2'-Deoxyguanosine monohydrate, 98+%

Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.

Solubility
Soluble in NH4OH 1 M: 50 mg/mL, clear to very faintly turbid.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Chemical Identifiers

CAS

961-07-9

Molecular Formula

C10H13N5O4

Molecular Weight (g/mol)

267.25

MDL Number

MFCD00150760

InChI Key

YKBGVTZYEHREMT-DWFKHXNSNA-N

Synonym

2'-deoxyguanosine, deoxyguanosine, guanine deoxyriboside, 2-deoxyguanosine, guanosine, 2'-deoxy, guanine deoxy nucleoside, 2'-deoxy-guanosine, 2;-deoxyguanosine, unii-g9481n71ro, guanine, 9-2-deoxy-beta-d-erythro-pentofuranosyl

PubChem CID

187790

ChEBI

CHEBI:17172

IUPAC Name

2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one

SMILES

NC1=NC2=C(N=CN2[C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)N1

Color

White

Quantity

10 g

Solubility Information

Soluble in NH4OH 1 M: 50mg/mL,clear to very faintly turbid.

Formula Weight

285.26 (267.25 Anhydrous)

Physical Form

Crystalline Powder

Chemical Name or Material

2'-Deoxyguanosine

EINECSNumber

213-505-8

TSCA

Yes

Recommended Storage

Ambient temperatures

SDS

EINECSNumber

213-505-8

TSCA

Yes

Recommended Storage

Ambient temperatures

SDS

RUO – Research Use Only