2-Thiouracil, 99%, Thermo Scientific Chemicals

2-Thiouracil, Thiouracil or 4-Hydroxy-2-mercaptopyrimidine, CAS # 141-90-2, is the modified analog of the nucleotide base, uracil.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• 2-Thiouracil (Thiouracil or 4-Hydroxy-2-mercaptopyrimidine) is a nucleotide analog with a C-2 thioxo substitution
• 2-Thiouracil is a melanocyte suppressor and thyroid inhibitor

Applications
• 2-Thiouracil can be used to inhibit nitric oxide synthase and suppresses nitric oxide signaling in vitro
• 2-Thiouracil can be used for labeling of RNA in vitro
• 2-Thiouracil is intended for research applications only

Chemical Identifiers

CAS

141-90-2

Molecular Formula

C4H4N2OS

Molecular Weight (g/mol)

128.15

MDL Number

MFCD00006039

InChI Key

ZEMGGZBWXRYJHK-UHFFFAOYSA-N

Synonym

2-thiouracil, thiouracil, 4-hydroxy-2-mercaptopyrimidine, antagothyroid, antagothyroil, deracil, nobilen, 2-thioxo-2,3-dihydropyrimidin-4 1h-one, 2-mercaptopyrimidin-4-ol, 2-mercapto-4-hydroxypyrimidine

PubChem CID

1269845

ChEBI

CHEBI:348530

IUPAC Name

2-sulfanylidene-1H-pyrimidin-4-one

SMILES

O=C1NC(=S)NC=C1

CAS Min %

98.5

CAS Max %

100.0

Melting Point

>300.0°C

Color

White to Cream

Loss on Drying

0.5% max. (105°C, 3 hrs)

Infrared Spectrum

Authentic

Assay Percent Range

98.5% min. (HPLC)

Packaging

Plastic bottle

Quantity

100 g

Beilstein

24, 323

Merck Index

15, 9520

Solubility Information

Solubility in water: 0.5g/L. Other solubilities: soluble in alkaline solutions

Formula Weight

128.15

Percent Purity

99%

Physical Form

Fine Crystalline Powder

Chemical Name or Material

2-Thiouracil

Hazard Category

GHS Signal Word: Warning

Hazard Statement

GHS H Statement:
Suspected of causing cancer.

Precautionary Statement

GHS P Statement:
Use personal protective equipment as required.

WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

EINECSNumber

205-508-8

SDS

Hazard Category

GHS Signal Word: Warning

Hazard Statement

GHS H Statement:
Suspected of causing cancer.

Precautionary Statement

GHS P Statement:
Use personal protective equipment as required.

WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

EINECSNumber

205-508-8

SDS

RUO – Research Use Only