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3,4-Dichloroisocoumarin, 98%, Thermo Scientific Chemicals

Catalog No. AAJ65198MA
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Useful in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors. It is an inhibitor of Chymotrypsin and Trypsin. ,4 Dichloroisocoumarin also inhibits granzymes A, B, and H, cathepsin G, neutrophil elastase, proteinase and blocks apoptotic internucleosomal DNA cleavage in thymocytes without the involvement of endonucleases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Useful in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors. It is an inhibitor of Chymot

Chemical Identifiers

CAS

51050-59-0

Molecular Formula

C9H4Cl2O2

Molecular Weight (g/mol)

215.03

MDL Number

MFCD00036960

InChI Key

SUGXUUGGLDCZKB-UHFFFAOYSA-N

Synonym

3,4-dichloroisocoumarin, 3,4-dcl, 1h-2-benzopyran-1-one,3,4-dichloro, 3,4-dci, 3,4 dichloroisocoumarin, 3,4-dichloro-1h-isochromen-1-one, 3,4-dichloro-1h-2-benzopyran-1-one, 1h-2-benzopyran-1-one, 3,4-dichloro, chembl24983, 3,4-dichloro-2-benzopyran-1-one

PubChem CID

1609

IUPAC Name

3,4-dichloroisochromen-1-one

SMILES

ClC1=C(Cl)C2=CC=CC=C2C(=O)O1

Specifications

Color

White

Quantity

10 mg

UN Number

UN2811

Beilstein

6802625

Solubility Information

Soluble in DMF or DMSO at a concentration of 10mM

Formula Weight

215.03

Percent Purity

99%

Physical Form

Powder

Chemical Name or Material

3,4-Dichloroisocoumarin

Hazard Category

H301-H315-H319-H335

Hazard Statement

GHS H Statement
H301-H315-H319-H335
Toxic if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

Precautionary Statement

P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c

DOTInformation

Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.

TSCA

No

Recommended Storage

Keep cold
SDS

RUO – Research Use Only

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