Thermo Scientific Chemicals 3'-Azido-3'-deoxythymidine, 98%

Description

Anti-viral agent

3'-Azido-3'-deoxythymidine is a Anti-viral agent, and also used as a reverse transcriptase inhibitor active against HIV-1 virus that blocks the incorporation of nucleotides into growing DNA strands. Useful for antiviral and anticancer studies. 3?-Azido-3?-deoxythymidine enters CNS by diffusion and causes irreversible telomere shortening.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3′-Azido-3′-deoxythymidine is a Anti-viral agent, and also used as a reverse transcriptase inhibitor active against HIV-1 virus that blocks the incorporation of nucleotides into growing DNA strands. Useful for antiviral and anticancer studies. 3′-Azido-3′-deoxythymidine enters CNS by diffusion and causes irreversible telomere shortening.

Solubility
Soluble in water.

Notes
Light Sensitive & Hygroscopic. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Specifications

Chemical Identifiers

• CAS: 30516-87-1
• Molecular Formula: C10H13N5O4
• Molecular Weight (g/mol): 267.25
• MDL Number: MFCD00006536
• InChI Key: HBOMLICNUCNMMY-CFQLRCIDNA-N
• Synonym: azt; azidothymidine; zdv; zidovudine, 1-2r-4-azido-5-hydroxymethyl oxolan-2-yl-5-methyl-3h-pyrimidine-2,4-dione
• PubChem CID: 455007
• SMILES: CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O

• Melting Point: 113°C to 115°C
• Color: White
• Quantity: 1 g
• Beilstein: 3595791
• Sensitivity: Light sensitive; Very Hygroscopic
• Merck Index: 1410123
• Solubility Information: Soluble in water.
• IUPAC Name: 1-[(2R,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
• Formula Weight: 267.24
• Percent Purity: 98%
• Physical Form: Powder
• Chemical Name or Material: 3'-Azido-3'-deoxythymidine

Safety and Handling

Hazard Category	Serious eye damage/eye irritation (category 2), Germ cell mutagenicity (category 2), Specific target organ toxicity after single exposure (category 3), Carcinogenicity (category 2), Skin corrosion/irritation (category 2)
Hazard Statement	Causes serious eye irritation, Suspected of causing genetic defects, May cause respiratory irritation, Suspected of causing cancer, Causes skin irritation
RTECSNumber	XP207200
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only