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3-MPPI, Tocris Bioscience™

Catalog No. p-4783182 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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Description

α1 ligand

Very potent ligand for α1 sites (Ki for displacement of prazosin = 0.2 nM). Displays different binding properties for each α1 subtype (pKi values are 8.74, 9.44 and 9.57 for α1B, α1D and α1A adrenoceptors respectively). Also binds to 5-HT1A sites (Ki = 50 nM).

Chemical Identifiers

CAS 133399-65-2
Molecular Formula C23H25N5O3
Molecular Weight (g/mol) 419.485
InChI Key AQASGOHUMGAWJJ-UHFFFAOYSA-N
Synonym 3-mppi, tocris-0581, biomol-nt_000127, 3-2-4-2-methoxyphenyl piperazino ethyl-1h-pyrimido 5,4-b indole-2,4 3h,5h-dione, 2-2-4-2-methoxy-phenyl-piperazin-1-yl-ethyl-4,9-dihydro-2,4,9-triaza-fluorene-1,3-dione, 3-2-4-2-methoxyphenyl piperazin-1-yl ethyl-1h-pyrimido 5,4-b indole-2,4 3h,5h-dione, 3-2-4-2-methoxyphenyl piperazin-1-yl ethyl-1,5-dihydropyrimido 5,4-b indole-2,4-dione, 3-2-4-2-methoxy-phenyl-piperazin-1-yl-ethyl-1,5-dihydro-pyrimido 5,4-b indole-2,4-dione
PubChem CID 4013695
IUPAC Name 3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1,5-dihydropyrimido[5,4-b]indole-2,4-dione
SMILES COC1=CC=CC=C1N2CCN(CC2)CCN3C(=O)C4=C(C5=CC=CC=C5N4)NC3=O

Specifications

Quantity 10 mg
Formula Weight 419.48
Percent Purity >98%
Chemical Name or Material 3-MPPI

Safety and Handling

Recommended Storage Store at Room Temperature
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