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4,4'-Diaminodiphenyl sulfone, 98%, Thermo Scientific Chemicals

Catalog No. AAA1897636
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It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy. It is a second-line medication for the treatment and prevention of Pneumocystis pneumonia and for the prevention of toxoplasmosis in those who have poor immune function. Additionally, it has been used for acne as well as other skin conditions. Moreover it is employed as an anti-inflammatory drug, anti-infective drug, a leprostatic drug and an antimalarial drug.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Insoluble in water. Solubility in hot methanol is almost transparent. Soluble in DMSO, ethanol and acetone.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Chemical Identifiers

CAS

80-08-0

Molecular Formula

C12H12N2O2S

Molecular Weight (g/mol)

248.3

MDL Number

MFCD00007887

InChI Key

MQJKPEGWNLWLTK-UHFFFAOYSA-N

Synonym

dapsone, diaphenylsulfone, 4,4'-diaminodiphenyl sulfone, dapson, 4,4'-sulfonyldianiline, diaphenylsulfon, sulfona, 4-aminophenyl sulfone, avlosulfone, diphenasone

PubChem CID

2955

ChEBI

CHEBI:4325

IUPAC Name

4-(4-aminophenyl)sulfonylaniline

SMILES

C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N

Specifications

Melting Point

175°C to 178°C

Odor

Odorless

Quantity

500 g

Beilstein

788055

Merck Index

14,2822

Solubility Information

Insoluble in water. Solubility in hot methanol is almost transparent. Soluble in DMSO,ethanol and acetone.

Formula Weight

248.3

Percent Purity

98%

Chemical Name or Material

4,4'-Diaminodiphenyl sulfone

Hazard Category

H302-H373

Hazard Statement

GHS H Statement
H302
Harmful if swallowed.

Precautionary Statement

P260-P264b-P270-P301+P312-P314-P330-P501c

EINECSNumber

201-248-4

RTECSNumber

BY8925000

TSCA

Yes

Recommended Storage

Ambient temperatures

RUO – Research Use Only

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