4-Bromo-4'-hydroxybiphenyl, 98%, Thermo Scientific Chemicals

Description

A biphenyl starting material. 4-Bromo-(1,1-biphenyl)-4-ol is a useful intermediate. Vinylation of 4-bromo-4-hydroxybiphenyl and ethyl acrylate using Pd (OAc) 2/PPh 3 catalyst was studied. Ethyl 4-(4-hydroxyphenyl) cinnamate was formed as the vinylation product, while, 4-hydroxybiphenyl and ethyl cinnamate were formed as side products. Preparation of 4-cyano-4'-hydroxybiphenyl This was prepared from 4-bromo-4'-benzenesulphonyloxybiphenyl by first hydrolysing it to 4-bromo-4-hydroxybiphenyl using sodium hydroxide dissolved in a mixture of water and dioxan. The syntheses of the Nanocomposite dendrimers based on cyclic phosphazene cores: Amorphous materials, were accomplished by following a modified literature procedure by reacting phosphonitrilic chloride trimer with 4-bromophenol or 4-bromo-4-hydroxybiphenyl, respectively, in the presence of K 2 CO 3 in tetrahydrofuran (THF).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
A biphenyl starting material. 4′-Bromo-(1,1′-biphenyl)-4-ol is a useful intermediate. Vinylation of 4-bromo-4′-hydroxybiphenyl and ethyl acrylate using Pd (OAc) 2/PPh 3 catalyst was studied. Ethyl 4-(4′-hydroxyphenyl) cinnamate was formed as the vinylation product, while, 4-hydroxybiphenyl and ethyl cinnamate were formed as side products. Preparation of 4-cyano-4′-hydroxybiphenyl This was prepared from 4-bromo-4′-benzenesulphonyloxybiphenyl by first hydrolysing it to 4-bromo-4-hydroxybiphenyl using sodium hydroxide dissolved in a mixture of water and dioxan. The syntheses of the Nanocomposite dendrimers based on cyclic phosphazene cores: Amorphous materials, were accomplished by following a modified literature procedure by reacting phosphonitrilic chloride trimer with 4-bromophenol or 4-bromo-4′-hydroxybiphenyl, respectively, in the presence of K 2 CO 3 in tetrahydrofuran (THF).

Solubility
Soluble in water (partly), and methanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 29558-77-8
• Molecular Formula: C12H9BrO
• Molecular Weight (g/mol): 249.107
• MDL Number: MFCD00059076
• InChI Key: ARUBXNBYMCVENE-UHFFFAOYSA-N
• Synonym: 4-bromo-4'-hydroxybiphenyl, 4'-bromo-1,1'-biphenyl-4-ol, 4-4-bromophenyl phenol, 4'-bromobiphenyl-4-ol, 4-hydroxy-4'-bromobiphenyl, 1,1'-biphenyl-4-ol, 4'-bromo, 4-bromo-4-hydroxybiphenyl, pubchem23025
• PubChem CID: 95093
• IUPAC Name: 4-(4-bromophenyl)phenol
• SMILES: C1=CC(=CC=C1C2=CC=C(C=C2)Br)O

• Melting Point: 163°C to 168°C
• Quantity: 5 g
• Solubility Information: Soluble in water (partly),and methanol.
• Formula Weight: 249.11
• Percent Purity: 98%
• Chemical Name or Material: 4-Bromo-4'-hydroxybiphenyl

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only