4-Bromobenzenesulfonyl chloride, 98+%, Thermo Scientific Chemicals

Description

4-Bromobenzenesulfonyl chloride is used as activating agent in the synthesis of oligodeoxyribo- and oligoribo- nucleotides in solution. It also used in the synthesis of 4-(N-allylsulfamoyl)phenylboronic acid and in protection of amines as 4-bromobenzenesulfonamides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Bromobenzenesulfonyl chloride is used as activating agent in the synthesis of oligodeoxyribo- and oligoribo- nucleotides in solution. It also used in the synthesis of 4-(N-allylsulfamoyl)phenylboronic acid and in protection of amines as 4-bromobenzenesulfonamides.

Solubility
Soluble in Tetrahydrofuran, petroleum ether and 1,4-dioxane. Insoluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Moisture sensitive. Store under inert gas.

Specifications

Chemical Identifiers

• CAS: 98-58-8
• Molecular Formula: C6H4BrClO2S
• Molecular Weight (g/mol): 255.51
• MDL Number: MFCD00007437
• InChI Key: KMMHZIBWCXYAAH-UHFFFAOYSA-N
• Synonym: 4-bromobenzene-1-sulfonyl chloride, p-bromobenzenesulfonyl chloride, 4-bromo-benzenesulfonyl chloride, p-bromophenylsulfonyl chloride, benzenesulfonyl chloride, 4-bromo, 4-bromobenzenesulphonyl chloride, 4-bromobenzenesulfonylchloride, unii-c6347t8fp1, 4-bromobenzene sulfonyl chloride, 4-bromophenyl chlorosulfone
• PubChem CID: 7396
• IUPAC Name: 4-bromobenzenesulfonyl chloride
• SMILES: C1=CC(=CC=C1S(=O)(=O)Cl)Br

• Melting Point: 73°C to 77°C
• Boiling Point: 152°C to 154°C (26 mmHg)
• Quantity: 25 g
• UN Number: UN3261
• Beilstein: 743518
• Sensitivity: Moisture sensitive
• Merck Index: 14,1407
• Solubility Information: Soluble in Tetrahydrofuran,petroleum ether and 1,4-dioxane. Insoluble in water.
• Formula Weight: 255.52
• Percent Purity: ≥98%
• Chemical Name or Material: 4-Bromobenzenesulfonyl chloride

Safety and Handling

Hazard Category	H314-H318
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber	202-683-2
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only