4-Methoxyphenylacetylene, 98%, Thermo Scientific Chemicals

Description

4-Ethynylanisole was used in the synthesis of photo luminescent 1,2-dihydrophosphinines via a [4 + 2] cycloaddition. Along with an arylboronic acid and sodium azide in a copper-catalyzed, three-component synthesis of trisubstituted 1,2,4-triazoles. In a study of a gold (III)-catalyzed hydroamination of alkynes leading to N-vinylindoles3.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Ethynylanisole was used in the synthesis of photo luminescent 1,2-dihydrophosphinines via a [4 + 2] cycloaddition. Along with an arylboronic acid and sodium azide in a copper-catalyzed, three-component synthesis of trisubstituted 1,2,4-triazoles. In a study of a gold (III)-catalyzed hydroamination of alkynes leading to N-vinylindoles3.

Solubility
Insoluble in water. Soluble in chloroform, acetone, dichloromethane, and methanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 768-60-5
• Molecular Formula: C9H8O
• Molecular Weight (g/mol): 132.162
• MDL Number: MFCD00168815
• InChI Key: KBIAVTUACPKPFJ-UHFFFAOYSA-N
• Synonym: 4-ethynylanisole, 4-methoxyphenylacetylene, 4'-methoxyphenyl acetylene, 1-ethynyl-4-methoxy-benzene, 1-eth-1-ynyl-4-methoxybenzene, benzene, 1-ethynyl-4-methoxy, 4-methoxyphenyl acetylene, 4-ethynyl-1-methoxybenzene, 4'-methoxyphenylacetylene, p-ethynylanisole
• PubChem CID: 251020
• IUPAC Name: 1-ethynyl-4-methoxybenzene
• SMILES: COC1=CC=C(C=C1)C#C

• Melting Point: 27°C to 29°C
• Density: 1.019
• Boiling Point: 87°C to 91°C (11 mmHg)
• Flash Point: 82°C (180°F)
• Refractive Index: 1.563
• Quantity: 1 g
• Solubility Information: Insoluble in water. Soluble in chloroform,acetone,dichloromethane,and methanol.
• Formula Weight: 132.16
• Percent Purity: 99%
• Chemical Name or Material: 4-Methoxyphenylacetylene

Safety and Handling

Hazard Category	H315-H319-H335-H500
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only