5-Chlorothiophene-2-sulfonyl chloride, 97%, Thermo Scientific Chemicals

5-Chlorothiophene-2-sulfonyl chloride is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuffs. It is used in the preparation of Notch-1-sparing γ-secretase inhibitors for the treatment of Alzheimer's disease.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Not miscible in water.

Notes
Moisture Sensitive. Store at 4°C. Incomaptible with oxidizing agents and bases.

Chemical Identifiers

CAS

2766-74-7

Molecular Formula

C4H2Cl2O2S2

Molecular Weight (g/mol)

217.08

MDL Number

MFCD00051667

InChI Key

SORSTNOXGOXWAO-UHFFFAOYSA-N

Synonym

5-chlorothiophene-2-sulfonylchloride, 5-chloro-2-thiophenesulfonyl chloride, 5-chlorothiophene-2-sulphonyl chloride, 5-chlorothiophenesulphonyl chloride, 5-chloro-2-thienylsulfonyl chloride, 5-chloro-thiophene-2-sulfonyl chloride, 5-chlorothiophenesulfonyl chloride, 5-chlorothiophen-2-sulfonyl chloride, 5-chlorothiophene-2-sulphonylchloride, 2-thiophenesulfonyl chloride, 5-chloro

PubChem CID

2733925

IUPAC Name

5-chlorothiophene-2-sulfonyl chloride

SMILES

ClC1=CC=C(S1)S(Cl)(=O)=O

Density

1.623

Boiling Point

117°C to 120°C (14 mmHg)

Flash Point

>110°C (230°F)

Refractive Index

1.586

Quantity

10 g

UN Number

UN3265

Beilstein

130710

Sensitivity

Moisture sensitive

Solubility Information

Not miscible in water.

Formula Weight

217.09

Percent Purity

97%

Chemical Name or Material

5-Chlorothiophene-2-sulfonyl chloride

Hazard Category

H314

Hazard Statement

GHS H Statement
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.

Precautionary Statement

P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

DOTInformation

Hazard Class: 8; Packaging Group: III

EINECSNumber

700-248-6

TSCA

No

Recommended Storage

Keep cold; Store under Nitrogen

SDS

Hazard Category

H314

Hazard Statement

GHS H Statement
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.

Precautionary Statement

P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

DOTInformation

Hazard Class: 8; Packaging Group: III

EINECSNumber

700-248-6

TSCA

No

Recommended Storage

Keep cold; Store under Nitrogen

SDS

RUO – Research Use Only