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5-Fluoro-2'-deoxyuridine, 98+%, Thermo Scientific Chemicals

Catalog No. AAL16497MC
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5-Fluoro-2'-deoxyuridine acts as an antiviral and antineoplastic agent. It is also employed for renal function diagnosis. Further, it is used as an experimental anticancer agent, which shows activity against a variety of malignant neoplasms. It is also used as an inhibitor of thymidylate synthetase and DNA synthesis. In addition to this, it plays an important role in the treatment of colorectal cancer.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water, alcohol, isopropyl alcohol, methanol, aqueous buffers, acetone, dimethyl sulfoxide, and ethanol. Insoluble in ether, benzene and chloroform.

Notes
Store in a cool place.Incompatible with strong oxidizing agents and strong bases.

Chemical Identifiers

CAS

50-91-9

Molecular Formula

C9H11FN2O5

Molecular Weight (g/mol)

246.19

MDL Number

MFCD00006530

InChI Key

ODKNJVUHOIMIIZ-RRKCRQDMSA-N

Synonym

floxuridine, 2'-deoxy-5-fluorouridine, 5-fluoro-2'-deoxyuridine, 5-fluorodeoxyuridine, fluorodeoxyuridine, floxuridin, fudr, deoxyfluorouridine, fluoruridine deoxyribose, fdurd

PubChem CID

5790

ChEBI

CHEBI:60761

IUPAC Name

5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

SMILES

OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(F)C(=O)NC1=O

Specifications

Melting Point

148°C to 151°C

Quantity

100 mg

UN Number

UN2811

Beilstein

2645818

Merck Index

14,4112

Solubility Information

Soluble in water,alcohol,isopropyl alcohol,methanol,aqueous buffers,acetone,dimethyl sulfoxide,and ethanol. Insoluble in ether,benzene and chloroform.

Formula Weight

246.2

Percent Purity

≥98%

Chemical Name or Material

5-Fluoro-2'-deoxyuridine

Hazard Category

H301-H315-H319-H341

Hazard Statement

GHS H Statement
H360-H341-H302
May damage fertility or the unborn child.
Suspected of causing genetic defects.
Harmful if swallowed.

Precautionary Statement

P201-P202-P264b-P270-P280i-P281-P301+P310-P302+P352-P305+P351+P338-P308+P313-P330-P332+P313-P362-P501c

DOTInformation

Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.

EINECSNumber

200-072-5

RTECSNumber

YU7535000

TSCA

No

Recommended Storage

Ambient temperatures
SDS

RUO – Research Use Only

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