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5-Fluorouracil, Tocris Bioscience™

Catalog No. 325750 Shop All R&D Systems Products
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Quantity:
50 mg
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This item is not returnable. View return policy

Description

Thymidylate synthetase inhibitor

Anticancer agent. Metabolized to form fluorodeoxyuridine monophosphate (FdUMP), fluorodeoxyuridine triphosphate (FdUTP) and fluorouridine (FUTP). FdUMP inhibits thymidylate synthase, causing a reduction in dTMP synthesis. FUTP and FdUTP are misincorporated into RNA and DNA respectively.

Chemical Identifiers

CAS 51-21-8
Molecular Formula C4H3FN2O2
Molecular Weight (g/mol) 130.08
MDL Number MFCD00006018
InChI Key GHASVSINZRGABV-UHFFFAOYSA-N
Synonym 5-fluorouracil, fluorouracil, 5-fu, fluoroplex, adrucil, efudex, carac, fluracil, fluoroblastin, kecimeton
PubChem CID 3385
ChEBI CHEBI:46345
IUPAC Name 5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione
SMILES FC1=CNC(=O)NC1=O

Specifications

Quantity 50 mg
Formula Weight 130.08
Percent Purity >99%
Chemical Name or Material 5-Fluorouracil

Safety and Handling

Recommended Storage Store at +4°C
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