5-Methylisoxazole-3-carboxylic acid, 98+%, Thermo Scientific Chemicals

Description

It is a reactant for Click/aza-Michael or Click/oligomeric alkyl carbodiimide esterification reactions, preparation of aminopyrazole amide derivatives as Raf kinase inhibitors in melanoma cells and preparation of trifluoromethoxyphenyl(thiazolyl)pyrroles and other heterocycle-bearing polyfunctionalized pyrroles via chain heterocyclization.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is a reactant for Click/aza-Michael or Click/oligomeric alkyl carbodiimide esterification reactions, preparation of aminopyrazole amide derivatives as Raf kinase inhibitors in melanoma cells and preparation of trifluoromethoxyphenyl(thiazolyl)pyrroles and other heterocycle-bearing polyfunctionalized pyrroles via chain heterocyclization.

Notes
Store at room temperature. Keep away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 3405-77-4
• Molecular Formula: C5H5NO3
• Molecular Weight (g/mol): 127.099
• MDL Number: MFCD01318162
• InChI Key: BNMPIJWVMVNSRD-UHFFFAOYSA-N
• Synonym: 5-methylisoxazole-3-carboxylic acid, 5-methylisoxazole-3-carboxylicacid, 3-isoxazolecarboxylic acid, 5-methyl, 5-methyl-3-isoxazolecarboxylic acid, 5-methyl-isoxazole-3-carboxylic acid, 3-carboxy-5-methylisoxazole, 3-isoxazolecarboxylicacid, 5-methyl, isoxazole acid, pubchem15552, ksc224c5p
• PubChem CID: 76947
• IUPAC Name: 5-methyl-1,2-oxazole-3-carboxylic acid
• SMILES: CC1=CC(=NO1)C(=O)O

• Melting Point: 171°C to 173°C
• Quantity: 5 g
• Beilstein: 114094
• Formula Weight: 127.1
• Percent Purity: ≥98%
• Chemical Name or Material: 5-Methylisoxazole-3-carboxylic acid

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	222-289-4
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only