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9-Fluorenylmethyl chloroformate, 98+%, Thermo Scientific Chemicals

Catalog No. AAA1168306
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Store cold

Base sensitive amino protecting group for solid-phase peptide synthesis9-Fluorenylmethyl chloroformate is used in capillary electrophoresis. It acts as a reagent in the precolumn derivatization of amines for HPLC and fluorescent detection. Further, it is used for derivatizing amino acids for HPLC analysis. In addition to this, it is used to prepare N-Fmoc amino acids for solid-phase peptide synthesis and oligonucleotide synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Base sensitive amino protecting group for solid-phase peptide synthesis9-Fluorenylmethyl chloroformate is used in capillary electrophoresis. It acts as a reagent in the precolumn derivatization of amines for HPLC and fluorescent detection. Further, it is used for derivatizing amino acids for HPLC analysis. In addition to this, it is used to prepare N-Fmoc amino acids for solid-phase peptide synthesis and oligonucleotide synthesis.

Solubility
Soluble in dioxane.

Notes
Moisture sensitive. Store in a cool place. Incompatible with alcohols and amines.

Chemical Identifiers

CAS

28920-43-6

Molecular Formula

C15H11ClO2

Molecular Weight (g/mol)

258.701

MDL Number

MFCD00001138

InChI Key

IRXSLJNXXZKURP-UHFFFAOYSA-N

Synonym

9-fluorenylmethyl chloroformate, fmoc-cl, fmoc-chloride, fmoc chloride, 9h-fluoren-9-ylmethyl chloroformate, carbonochloridic acid, 9h-fluoren-9-ylmethyl ester, 9-fluorenylmethoxycarbonyl chloride, 9-fluorenylmethylchloroformate, 9h-fluoren-9-yl methyl carbonochloridate, 9h-fluoren-9-ylmethoxy carbonyl chloride

PubChem CID

34367

IUPAC Name

9H-fluoren-9-ylmethyl carbonochloridate

SMILES

C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)Cl

Specifications

Melting Point

60°C to 64°C

Assay Percent Range

98%

Quantity

5 g

UN Number

UN2923

Beilstein

2279177

Sensitivity

Moisture sensitive

Solubility Information

Soluble in dioxane.

Formula Weight

258.7

Percent Purity

98%

Chemical Name or Material

9-Fluorenylmethyl Chloroformate

Hazard Category

H302+H312+H332-H314-H335

Hazard Statement

GHS H Statement
H314-H318-H302-H332

Precautionary Statement

P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c

DOTInformation

Hazard Class: 6.1; Packaging Group: II

EINECSNumber

249-313-6

RTECSNumber

LQ6250000

TSCA

No

storageNote1

Moisture Sensitive

Recommended Storage

Keep cold; Store under Nitrogen
SDS

RUO – Research Use Only

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