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  8. A 77636 hydrochloride, Tocris Bioscience™

A 77636 hydrochloride, Tocris Bioscience™

Catalog No. p-4783701 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective D1-like agonist; orally active

Potent and selective dopamine D1-like receptor agonist (pEC50 values are 8.97 and < 5 for D1-like and D2-like receptors respectively). Displays anti-Parkinsonian activity following oral administration in vivo. Exhibits 11-fold cell type bias over dopamine in a functional assay in U2 cells.

Chemical Identifiers

CAS 145307-34-2
Molecular Formula C20H28ClNO3
Molecular Weight (g/mol) 365.898
InChI Key BWHPNJVKFAPVOG-UHFFFAOYSA-N
Synonym (1R-cis)-1-(Aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-[1H]-2-benzopyran-5,6-diol hydrochloride
PubChem CID 16069211
IUPAC Name 3-(1-adamantyl)-1-(aminomethyl)-3,4-dihydro-1H-isochromene-5,6-diol;hydrochloride
SMILES C1C2CC3CC1CC(C2)(C3)C4CC5=C(C=CC(=C5O)O)C(O4)CN.Cl

Specifications

Quantity 10 mg
Formula Weight 365.9
Percent Purity >98%
Chemical Name or Material A 77636 hydrochloride

Safety and Handling

Recommended Storage Desiccate at +4°C
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