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  8. A 803467, Tocris Bioscience™

A 803467, Tocris Bioscience™

Catalog No. p-4783702 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Selective NaV1.8 channel blocker

Selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively). Shows no significant activity against TRPV1, P2X2/3, CaV2.2 and KCNQ2/3 channels. Antinociceptive; potently attenuates mechanical allodynia in two models of neuropathic pain following i.p. administration.

Chemical Identifiers

CAS 944261-79-4
Molecular Formula C19H16ClNO4
Molecular Weight (g/mol) 357.79
MDL Number MFCD10574689
InChI Key VHKBTPQDHDSBSP-UHFFFAOYSA-N
PubChem CID 16038374
IUPAC Name 5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide
SMILES COC1=CC(OC)=CC(NC(=O)C2=CC=C(O2)C2=CC=C(Cl)C=C2)=C1

Specifications

Quantity 10 mg
Synonym 5-4-chlorophenyl-n-3,5-dimethoxyphenyl furan-2-carboxamide, 5-4-chlorophenyl-n-3,5-dimethoxyphenyl-2-furancarboxamide, d0ff6s, 2-furancarboxamide, 5-4-chlorophenyl-n-3,5-dimethoxyphenyl, 5-4-chlorophenyl-n-3,5-dimethoxyphenyl, 5-4-chlorophenyl-furan-2-carboxylic acid 3,5, a hplc, 5-4-chlorophenyl-n-3,5-dimethoxyphenyl-2-furamide, 2-furancarboxamide,5-4-chlorophenyl-n-3,5-dimethoxyphenyl
Formula Weight 357.79
Percent Purity >98%
Chemical Name or Material A 803467

Safety and Handling

Recommended Storage Store at +4°C
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