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Tocris Bioscience™ Ac4ManNAz

Catalog No. 747910 Shop All R&D Systems Products
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10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Azide-containing monosaccharide building block; used as glycoprotein, glycolipid and glycoRNA probe

Ac4ManNAz is a cell-permeable, unnatural azide-containing monosaccharide building block. Ac4ManNAz is metabolized and incorporated as azidosialic acid into cell surface and secreted sialoglycoproteins to allow Cu(I)-free click chemistry for further conjugation or detection. Ac4ManNAz can be used for bioorthogonal labeling of human prostate tissue slice cultures; the target sialoglycoproteins can be biotinylated for proteomic analysis or reacted with a cyclooctyne-functionalized optical probe for imaging. Ac4ManNAz is also used to label glycoRNAs on the cell surface.

Specifications

Chemical Name or Material 2-[(2-Azidoacetyl)amino]-2-deoxy-D-mannopyranose-1,3,4,6-tetraacetate
CAS 361154-30-5
Quantity 10 mg
Target Photoactivatable Cross-linking Probes
Molecular Formula C16H22N4O10
Purity 0.95
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