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Adapalene, Tocris Bioscience™

Catalog No. p-4783721 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

RARβ and RARγ agonist

Retinoic acid analog that is a RARβ and RARγ agonist (AC50 values are 2.2, 9.3, 22 and > 1000 nM for RARβ, RARγ, RARα and RXRα receptors respectively). Inhibits proliferation and induces apoptosis in colorectal cancer cell in vitro. Displays comedolytic activity.

Chemical Identifiers

CAS 106685-40-9
Molecular Formula C28H28O3
Molecular Weight (g/mol) 412.529
InChI Key LZCDAPDGXCYOEH-UHFFFAOYSA-N
Synonym adapalene, differin, adapalenum, adapaleno, adapaleno inn-spanish, adaferin, 6-3-adamantan-1-yl-4-methoxyphenyl-2-naphthoic acid, adapalenum inn-latin, differine, 6-3-1-adamantyl-4-methoxyphenyl-2-naphthoic acid
PubChem CID 60164
ChEBI CHEBI:31174
IUPAC Name 6-[3-(1-adamantyl)-4-methoxyphenyl]naphthalene-2-carboxylic acid
SMILES COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5

Specifications

Quantity 10 mg
Formula Weight 412.52
Percent Purity >98%
Chemical Name or Material Adapalene

Safety and Handling

Recommended Storage Store at +4°C
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