Thermo Scientific Chemicals Adenosine-3',5'-cyclic monophosphate, 98%

Description

cAMP is used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent pathway. Restoration of several morphological characteristics of normal fibroblasts in sarcoma cells when treated with adenosine-3?: 5?-cyclic monophosphate. In the presence of adenosine 3?:5?-cyclic monophosphate, protein kinase I dissociated into two subunits: a subunit binding adenosine 3?:5?-cyclic monophosphate, and a catalytic subunit. Stimulation of calcium uptake in platelet membrane vesicles by adenosine 3?,5?-cyclic monophosphate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
cAMP is used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent pathway. Restoration of several morphological characteristics of normal fibroblasts in sarcoma cells when treated with adenosine-3′: 5′-cyclic monophosphate. In the presence of adenosine 3′:5′-cyclic monophosphate, protein kinase I dissociated into two subunits: a subunit binding adenosine 3′:5′-cyclic monophosphate, and a catalytic subunit. Stimulation of calcium uptake in platelet membrane vesicles by adenosine 3′,5′-cyclic monophosphate.

Solubility
Solube in water: 10 mg/mL pH of aqueous solution is approx. 3.0.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 60-92-4
• Molecular Formula: C10H12N5O6P
• Molecular Weight (g/mol): 329.21
• MDL Number: MFCD00005845
• InChI Key: IVOMOUWHDPKRLL-YPLCUDRINA-N
• Synonym: camp, cyclic amp, adenosine 3',5'-cyclic monophosphate, 3',5'-cyclic amp, adenosine 3',5'-phosphate, adenosine 3',5'-cyclophosphate, cyclic 3',5'-amp, adenosine cyclic monophosphate, adenosine-3',5'-cyclophosphate, cyclic adenosine monophosphate
• PubChem CID: 6076
• ChEBI: CHEBI:17489
• IUPAC Name: (4aR,6R,7R,7aS)-6-(6-aminopurin-9-yl)-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
• SMILES: NC1=C2N=CN([C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O)C2=NC=N1

• Melting Point: 260°C (decomposition)
• Color: White
• Quantity: 1 g
• Beilstein: 52645
• Merck Index: 14,2708
• Solubility Information: Solube in water: 10mg/mL pH of aqueous solution is approx. 3.0.
• Formula Weight: 329.21
• Percent Purity: 98%
• Physical Form: Crystalline Powder
• Chemical Name or Material: Adenosine-3',5'-cyclic monophosphate

Safety and Handling

Hazard Category	H314-H500
Precautionary Statement	P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
DOTInformation	Hazard Class: 8; Packaging Group: III
EINECSNumber	200-492-9
RTECSNumber	AU7357600
TSCA	Yes
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only