Adenosine Deaminase Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA551572

Catalog No. PIPA551572

Description

Immunogen sequence: GDETIPGSSL LPGHVQAYQE AVKSGIHRTV HAGEVGSAEV VKEAVDILKT ERLGHGYHTL EDQALYNRLR QENMHFEICP WSSYLTGAWK PDTEHAVIRL KNDQANYSLN TDDPLIFKST LDTDYQMTKR DMGFTEEE Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 83%.

Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.

Specifications

• Antigen: Adenosine Deaminase
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADA
• Gene Alias: RP11-61L14.5, ADAR1, DRADA, DSH, DSRAD, G1P1, IFI-4, IFI4, K88DSRBP, P136, 136 kDa double-stranded RNA-binding protein, adenosine deaminase acting on RNA 1-A, double-stranded RNA-specific adenosine deaminase, dsRNA adenosine deaminase, interferon-induced protein 4, interferon-inducible protein 4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100, 11486, 24165
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P00813, P03958, Q920P6
• Gene Symbols: ADA
• Immunogen: Recombit protein corresponding to Human Adenosine Deaminase
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Research Use Only