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Alantolactone, Tocris Bioscience™

Catalog No. 449050 Shop All R&D Systems Products
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Antiproliferative; induces activin/Smad3 signaling

Sesquiterpene lactone. Induces activin/SMAD3 signaling and disrupts Cripto-1/activin receptor type II A interaction. Displays antiproliferative activity in human colon adenocarcinoma HCT-8 cells.

Chemical Identifiers

CAS

546-43-0

Molecular Formula

C15H20O2

Molecular Weight (g/mol)

232.32

MDL Number

MFCD00274568

InChI Key

PXOYOCNNSUAQNS-AGNJHWRGSA-N

Synonym

alantolactone, helenine, eupatal, alant camphor, inula camphor, helenin, elecampane camphor, unii-m7gsn5q1m6, m7gsn5q1m6, 3ar,5s,8ar,9ar-5,8a-dimethyl-3-methylidene-3a,5,6,7,8,8a,9,9a-octahydronaphtho 2,3-b furan-2 3h-one

PubChem CID

72724

ChEBI

CHEBI:2540

IUPAC Name

(3aR,5S,8aR,9aR)-5,8a-dimethyl-3-methylidene-2H,3H,3aH,5H,6H,7H,8H,8aH,9H,9aH-naphtho[2,3-b]furan-2-one

SMILES

C[C@H]1CCC[C@]2(C)C[C@H]3OC(=O)C(=C)[C@H]3C=C12

Specifications

Quantity

50 mg

Formula Weight

232.32

Percent Purity

>98%

Chemical Name or Material

Alantolactone

Recommended Storage

Store at -20°C
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