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  8. AMD 3465 hexahydrobromide, Tocris Bioscience™

AMD 3465 hexahydrobromide, Tocris Bioscience™

Catalog No. p-4817368 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Potent and selective CXCR4 antagonist

Potent, selective CXCR4 antagonist; exhibits 8-fold higher affinity than AMD 3100 (Cat.No. 3299). Inhibits SDF-1α-ligand binding (Ki = 41.7 nM). Potently inhibits HIV cell entry in vitro; causes leukocytosis and mobilizes haematopoietic stem cells in vivo.

Chemical Identifiers

CAS 185991-07-5
Molecular Formula C24H44Br6N6
Molecular Weight (g/mol) 896.082
InChI Key ARHBIBDGWDRBJH-UHFFFAOYSA-N
Synonym amd 3465 hexahydrobromide, pyridin-2-ylmethyl 4-1,4,8,11-tetraazacyclotetradecan-1-ylmethyl phenyl methyl amine hexahydrobromide, n-4-1,4,8,11-tetraazacyclotetradec-1-ylmethyl phenyl methyl-2-pyridinemethanamine hexahydrobromide, amd3465 hexahydrobromide, amd3465 6 hbr, n-pyridin-2-ylmethyl-1-4-1,4,8,11-tetrazacyclotetradec-1-ylmethyl phenyl methanamine hexahydrobromide
PubChem CID 9897616
IUPAC Name N-(pyridin-2-ylmethyl)-1-[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methanamine;hexahydrobromide
SMILES C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CNCC3=CC=CC=N3.Br.Br.Br.Br.Br.Br

Specifications

Quantity 10 mg
Formula Weight 896.07
Percent Purity >97%
Chemical Name or Material AMD 3465 hexahydrobromide

Safety and Handling

Recommended Storage Store at -20°C
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