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Amikacin (From Kanamycin A, White Crystalline Powder), Fisher BioReagents

Catalog No. p-24173
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  • An antibiotic that serves as a selective agent to isolate transformed bacteria
  • Amikacin functions as an indirect inhibitor of protein synthesis in prokaryotes by binding to the 30S subunit of ribosomes
  • Useful as a selective agent to isolate bacteria that have been transformed with plasmid containing the antibiotic-resistant gene
  • Intended for research purposes only; not for manufacturing or commercial use

Chemical Identifiers

CAS

37517-28-5

Molecular Formula

C22H43N5O13

Molecular Weight (g/mol)

585.608

InChI Key

LKCWBDHBTVXHDL-RMDFUYIESA-N

Synonym

Lukadin

PubChem CID

37768

ChEBI

CHEBI:2637

IUPAC Name

(2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide

SMILES

C1C(C(C(C(C1NC(=O)C(CCN)O)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)O)N

Specifications

Type

Amikacin

Physical Form

Solid

pH

9.5 to 11.5

Melting Point

214°C

Packaging

Amber Glass

Potency

> 900μg/mg

Color

White

Quantity

1 g

Merck Index

15, 400

Solubility Information

completely soluble in water

Formula Weight

585.61

Chemical Name or Material

Amikacin, From Kanamycin A

Hazard Statement

CAUTION!

Precautionary Statement

Emergency Overview
May cause skin, eye, and respiratory tract irritation. Use personal protective equipment. Ensure adequate ventilation. Wash off immediately with plenty of water for at least 15 minutes. Get medical attention immediately if symptoms occur. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Obtain medical attention. Move to fresh air. If breathing is difficult, give oxygen. Get medical attention immediately if symptoms occur. Do not induce vomiting. Obtain medical attention. Obtain medical attention. .

NFPA

Health:1
Flammability:0
Instability:0

TSCA

Not on TSCA inventory: for R and D use only; not for manufacturing or commercial purposes.

Recommended Storage

0° to 5°C, desiccate.

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