Amlodipine, 97+%, Thermo Scientific Chemicals

Description

A calcium channel antagonist with potent antioxidant activity

A calcium channel antagonist with potent antioxidant activityAmlodipine is an L-type calcium channel protein inhibitor and blocker. It is used in combination with the angiotensin receptor blocker olmesartan. Further, it acts as a dihydropyridine calcium channel blocker. It is used as an anti-hypertensive. It is involved in the treatment of angina and to lower blood pressure. In addition to this, it is used to prevent chest pain and in coronary artery disease.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in dimethyl sulfoxide, ethanol, water, dimethyl formamide, acetone, chloroform, ethyl acetate and methanol.

Notes
Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 88150-42-9
• Molecular Formula: C20H25ClN2O5
• Molecular Weight (g/mol): 408.88
• MDL Number: MFCD00864687
• InChI Key: HTIQEAQVCYTUBX-UHFFFAOYNA-N
• Synonym: amlodipine, norvasc, amlodis, amlodipino, amlodipinum, amlocard, coroval, lipinox, amlor, amlodipinum latin
• PubChem CID: 2162
• ChEBI: CHEBI:2668
• IUPAC Name: 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
• SMILES: CCOC(=O)C1=C(COCCN)NC(C)=C(C1C1=CC=CC=C1Cl)C(=O)OC

• Melting Point: 134°C to 136°C
• Color: White
• Quantity: 1 g
• UN Number: UN2811
• Merck Index: 14,491
• Solubility Information: Soluble in dimethyl sulfoxide,ethanol,water,dimethyl formamide,acetone,chloroform,ethyl acetate and methanol.
• Formula Weight: 408.88
• Percent Purity: ≥97%
• Physical Form: Crystalline Powder
• Chemical Name or Material: Amlodipine

Safety and Handling

Hazard Category	H301-H318-H373
Hazard Statement	GHS H Statement H301-H318-H373 Toxic if swallowed. Causes serious eye damage. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statement	P260-P264b-P270-P280-P301+P310-P305+P351+P338-P310-P314-P330-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber	425-820-1
RTECSNumber	US7968329
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only