MilliporeSigma™ anti-APC Clone: CC-1,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ OP80100UG

Catalog No. OP80100UG

Description

Specifically detects APC Clone: CC-1 in Human, Mouse, Rat samples, and it is validated for Immunocytochemistry, Immunofluorescence

Germ line mutations in the APC gene are responsible for familial adenomatous polyposis and somatic mutations contribute to sporadic colorectal cancer. The 312kDa APC protein is expressed in all tissues and localized to the cytoskeletal architecture in an insoluble complex with β-catenin. The APC (Ab-7) mouse monoclonal antibody clone CC-1 decorates oligodendrocyte cell bodies, purkinje cells, astrocytes, and optic nerve cell bodies of formalin-fixed, paraffin-embedded, or fresh frozen sections from human, mouse, and rat brain. Dectection of APC (Ab-7) can be perfomed using immunofluorescence or immunohistochemistry techniques.

Specifications

• Antigen: APC
• Clone: CC-1
• Formulation: In 50mM sodium phosphate buffer, 0.2% gelatin.
• Host Species: Mouse
• Isotype: IgG2b
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes APC in oligodendrocytes and astrocytes. Antibody Target Gene Symbol: APC Target Synonym: AI047805, Apc7, AU020952, AW124434, BTPS2, DP2, DP2.5, DP3, Familial adenomatous polyposis, FAP, GS, Min, RATAPC Entrez Gene Name: adenomatous polyposis coli

• Applications: Immunocytochemistry, Immunofluorescence
• Conjugate: Unconjugated
• Format: Purified
• Immunogen: a recombinant protein consisting of amino acids 1-226 of APC
• Quantity: 100μg
• Storage Requirements: 2°C to 8°C
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Human, Mouse, Rat

For Research Use Only