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  8. AZM 475271, Tocris Bioscience™

AZM 475271, Tocris Bioscience™

Catalog No. p-4816852 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Src tyrosine kinase inhibitor

Src tyrosine kinase inhibitor. Reduces tumor size, vascularity and metastasis, and increases apoptosis in human pancreatic cells grown in nude mice. Also exhibits antiangiogenic activity in vitro and in vivo. Sensitizes tumor cells to the cytotoxic effects of gemcitabine (Cat. No. 3259).

Chemical Identifiers

CAS 476159-98-5
Molecular Formula C23H27ClN4O3
Molecular Weight (g/mol) 442.944
InChI Key WPOXAFXHRJYEIC-UHFFFAOYSA-N
Synonym n-2-chloro-5-methoxyphenyl-6-methoxy-7-1-methylpiperidin-4-yl methoxy quinazolin-4-amine, methoxy aniline 7, azd0530 analogue 35, 4-quinazolinamine, n-2-chloro-5-methoxyphenyl-6-methoxy-7-1-methyl-4-piperidinyl methoxy, n-2-chloro-5-methoxyphenyl-6-methoxy
PubChem CID 5330175
IUPAC Name N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
SMILES CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=CC(=C4)OC)Cl)OC

Specifications

Quantity 10 mg
Formula Weight 442.94
Percent Purity >99%
Chemical Name or Material AZM 475271

Safety and Handling

Recommended Storage Store at Room Temperature
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