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Tocris Bioscience™ Bax channel blocker

Allosteric inhibitor of Bax channel activation

Supplier:  Tocris Bioscience™ 2160/10

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Catalog No. 21-601-0R


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Description

Description

Bax channel blocker is a allosteric inhibitor of Bax channel activation. Binds inactive Bax at allosteric site and inhibits tBID-mediated Bax activation (IC50 = 3.3 μM). Selectively inhibits Bax-dependent apoptosis. Potent inhibitor of Bax-mediated mitochondrial cytochrome c release (IC50 = 0.52 μM).
Specifications

Specifications

>98%
Bax channel blocker
Bax channel blocker
10 mg
540.12
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